Sonographic prognostic factors in fetuses with sacrococcygeal teratoma

Westerburg, Bettina; Feldstein, Vickie A.; Sandberg, Per; Lopoo, John B.; Harrison, Michael R.; Albanese, Craig T.

doi:10.1016/s0022-3468(00)90032-0

Cited by 103 publications

(96 citation statements)

References 11 publications

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“…Interestingly, these 2 cases show that fetuses with hydrops from CHAOS can survive many weeks in utero. This is in contrast to hydrops associated with sacrococcygeal teratoma or congenital cystic adenomatoid malformation of the lung, which most often leads to early fetal death [13]. Further observations of the natural history of CHAOS are needed to determine the risk of early fetal demise in these cases.…”

Section: Discussionmentioning

confidence: 96%

Successful Fetal Intervention for Congenital High Airway Obstruction Syndrome

Paek¹,

Kitterman

Feldstein³

et al. 2002

Fetal Diagn Ther

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Introduction: Complete congenital high airway obstruction syndrome (CHAOS) usually leads to stillbirth or death within minutes of delivery. We describe the management and long-term follow-up of a baby with a prenatally diagnosed airway obstruction. Case: Because of progressive hydrops fetalis, massive ascites and everted diaphragms due to CHAOS in a fetus at 24 weeks of gestation, a fetal tracheostomy was performed. Persistent fetal bradycardia at the time of the fetal procedure led to delivery of the infant. Adequate oxygenation and ventilation were attained using relatively low oxygen concentrations and low ventilatory pressures. Plain radiographs demonstrated that the lungs were large and the ribs thin. The infant has a permanent tracheostomy, required continuous assisted ventilation for several months and assisted ventilation at night at home for 3 years. At 4 years of age, he has no speech, all feedings are by gastrostomy, and developmentally he is mildly to moderately delayed. Conclusion: Laryngeal atresia produced over-distended lungs and hydrops. Precise prenatal imaging and fetal surgical strategies may allow the survival of affected fetuses.

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Section: Discussionmentioning

confidence: 96%

Successful Fetal Intervention for Congenital High Airway Obstruction Syndrome

Paek¹,

Kitterman

Feldstein³

et al. 2002

Fetal Diagn Ther

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“…Fetal hidrops, büyü-yen tümörün vasküler kaçağı sonucu yüksek outputlu kalp yetmezliğine bağlı olarak ortaya çıkar (6). Ultrasonografide solid komponent hakimiyeti olan ve artmış vaskülarizasyonu olan teratomlu fetuslarda in utero hidrops gelişme riski yüksektir (7). Sakrokoksigeal teratomla doğan infantların prognozu gestasyonel yaşla korelasyon gösterir.…”

Section: Discussionunclassified

Fetal Sakrokoksigeal Teratom-Prenatal Tanı ve Yönetim Olgu Sunumu

Ruşen;ENGİN¹

2002

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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“…Furthermore, the mother may develop mirror syndrome. The groups from UCSF and CHOP demonstrated that fetal hydrops and placentomegaly are indicators of poor outcome (Bond et al, 1990;Westerburg et al, 2000). Others have proposed additional prognostic criteria such as rate of tumour growth based on which fetal intervention may be considered (Westerburg et al, 2000).…”

Section: Sacrococcygeal Teratomamentioning

confidence: 99%

The making of fetal surgery

et al. 2010

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Fetal diagnosis prompts the question for fetal therapy in highly selected cases. Some conditions are suitable for in utero surgical intervention. This paper reviews historically important steps in the development of fetal surgery. The first invasive fetal intervention in 1963 was an intra-uterine blood transfusion. It took another 20 years to understand the pathophysiology of other candidate fetal conditions and to develop safe anaesthetic and surgical techniques before the team at the University of California at San Francisco performed its first urinary diversion through hysterotomy. This procedure would be abandoned as renal and pulmonary function could be just as effectively salvaged by ultrasound-guided insertion of a bladder shunt. Fetoscopy is another method for direct access to the feto-placental unit. It was historically used for fetal visualisation to guide biopsies or for vascular access but was also abandoned following the introduction of high-resolution ultrasound. Miniaturisation revived fetoscopy in the 1990s, since when it has been successfully used to operate on the placenta and umbilical cord. Today, it is also used in fetuses with congenital diaphragmatic hernia (CDH), in whom lung growth is triggered by percutaneous tracheal occlusion. It can also be used to diagnose and treat urinary obstruction. Many fetal interventions remain investigational but for a number of conditions randomised trials have established the role of in utero surgery, making fetal surgery a clinical reality in a number of fetal therapy programmes. The safety of fetal surgery is such that even non-lethal conditions, such as myelomeningocoele repair, are at this moment considered a potential indication. This, as well as fetal intervention for CDH, is currently being investigated in randomised trials.

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Sonographic prognostic factors in fetuses with sacrococcygeal teratoma

Cited by 103 publications

References 11 publications

Successful Fetal Intervention for Congenital High Airway Obstruction Syndrome

Successful Fetal Intervention for Congenital High Airway Obstruction Syndrome

Fetal Sakrokoksigeal Teratom-Prenatal Tanı ve Yönetim Olgu Sunumu

The making of fetal surgery

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