Sonographic scoring of solid thyroid nodules: effects of nodule size and suspicious cervical lymph node

Abstract

Sonographic scoring of thyroid nodules is an effective method for predicting malignancy. The authors suggest including associated pathologic node in the scoring criteria. Further studies with larger cohorts will provide more evidence about its importance in sonographic scoring.

Nomogram for the diagnosis of suspected papillary thyroid carcinomas based on sonographic patterns: a retrospective study

“…The US features for PTCs included in our present study were based on the ATA guidelines (2) and other previous related studies (1,11,14). Previous studies have shown that several US features, such as nodular margins, blood flow distribution, hypoechoic appearance, and microcalcification are associated with PTC malignancy, which was consistent with our multivariate analysis (15,16).…”

“…Ultrasonographic-guided FNAB is used to diagnose suspicious nodules for thyroid cancer (2). However, there are some disadvantages, such as inadequate sampling, high cost, invasiveness, indeterminate cytology in some cases, and operator dependency (13,14). Thus, accurate PTC diagnosis using only US is very valuable.…”

“…In our analysis, we included 25 factors that are reported to possibly be related to the risk of PTC (14,20). However, our result detected only US features that can be used to distinguish benign nodules and PTCs.…”

A Proposal to Stratify the Intermediate-Risk Thyroid Nodules According to the AACE/ACE/AME Guidelines with Ultrasound Features

“…In the present study, nodule was smaller in malignant group than in benign group. When divided them into two groups by 20 mm, there was no statistically significantly difference in malignancy rate, which was similar to Unsal’s result 17 . Therefore, nodule size was excluded from independent risk factors of intermediate-risk TNs in binary multivariate logistic regression analysis in our study.…”

“…By contrast, Unsal et al . 17 thought nodule size ≥2 cm was not distinctive for diagnosis of malignancy. In the present study, nodule was smaller in malignant group than in benign group.…”