Sonography of polyhydramnios

Alexander, Eben; Spitz, Harold B.; Clark, R A

doi:10.2214/ajr.138.2.343

Cited by 23 publications

(13 citation statements)

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“…Polyhydramnios was a presenting clinical manifestation of fetal goiter in this case and the one described by Barone et al [7], While most cases of polyhydramnios are unex plained, 21 % arc associated with fetal abnor malities [8], Functional or structural abnor malities in fetal central nervous system, gas trointestinal tract, or heart account for over 80% of these cases [8]. With goiter, polyhy dramnios is likely due to mechanical inter ference with swallowing.…”

Section: Discussionsupporting

confidence: 60%

Fetal Goitrous Hypothyroidism

Johnson¹,

Finberg²,

Perelman³

et al. 1989

Fetal Diagn Ther

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We present a first case in whom fetal hypothyroidism with goiter was both successfully diagnosed and treated in utero. An obstetrical sonogram at 33 weeks revealed a bilobed fetal neck mass, compatible with enlarged thyroid gland, associated with neck hyperextension, reduced gastric fluid, and polyhydramnios. Umbilical blood sampling after volume reduction amniocentesis confirmed fetal hypothyroidism with a euthyroid mother. Fetal T₄ measured 1.3 μg/dl, free T₄ 0.3 ng/dl, and thyroidstimulating hormone 186 μU. Intra-amniotic levothyroxine, 500 μg, was given twice with a 14-day interval. The head flexed, gastric fluid increased, and amniotic fluid levels returned to normal. Prenatal (36 weeks) and neonatal blood sampling demonstrated return to euthyroid indices. Ultrasonic estimates of thyroid volume decreased by over 50%. Vaginal delivery at 39 weeks was incomplicated. The newborn appeared normal and is being maintained on thyroid replacement therapy.

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Section: Discussionsupporting

confidence: 60%

Fetal Goitrous Hypothyroidism

Johnson¹,

Finberg²,

Perelman³

et al. 1989

Fetal Diagn Ther

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“…Alexander et al [3] found that polyhydramnios in 1 32 patients was idiopathic (62%), secondary to maternal disease (20%), and associated with fetal anomalies (18%). Queenan's review of 358 patients [1 5] …”

Section: Discussionmentioning

confidence: 99%

Severe polyhydramnios: incidence of anomalies

Barkin¹,

Pretorius²,

Beckett³

et al. 1987

American Journal of Roentgenology

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“…The cited incidence of hydramnios is between 0.1 and 1.6% [ 1.2], these data being based in most studies on clin ical evaluations [2][3][4], With the increase of the use of ultrasound (US) in obstetrics, the diagnosis of hydram nios has become easier and more accurate. Furthermore, with the progress of modern obstetrics and the improve ment of antenatal care, the significance of some of the major causes of hydramnios as quoted by Queenan and Gadow [3], such as diabetes mellitus and RH incompati bility, has declined.…”

Section: Introductionmentioning

confidence: 99%

Hydramnios in Singleton Pregnancy: Sonographic Prevalence and Etiology

Golan

Wolman²,

Saller³

et al. 1993

Gynecol Obstet Invest

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One hundred and forty-nine cases of hydramnios were detected among 13,750 parturients undergoing 25,000 routine ultrasonographic examinations. The prevalence of hydramnios was 1.08%. Ninety-seven patients (65.1 %) had no apparent cause for the increased amount of fluid volume. Twenty-eight new-borns (18.8%) were congenitally malformed, and 22 (14.8%) patients had diabetes mellitus. Rh incompatibility accounted for only 1.3% of the cases. It seems that with the improvement of modern obstetrics, mainly improving the antenatal management of diabetes and Rh incompatibility, there is a decrease in the relative incidence of these two conditions as etiological factors of hydramnios.

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Sonography of polyhydramnios

Cited by 23 publications

References 0 publications

Fetal Goitrous Hypothyroidism

Fetal Goitrous Hypothyroidism

Severe polyhydramnios: incidence of anomalies

Hydramnios in Singleton Pregnancy: Sonographic Prevalence and Etiology

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