The effect of treatment for primary prostatic lesions of Stage D2 prostatic cancer was evaluated by means of transrectal ultrasonotomography and was compared with that for distant metastatic lesions. A new score system was introduced to assess the effect of treatment for the primary lesions of prostatic cancer from the ultrasonic findings of the prostate on a single examination after treatment. In 19 subjects evaluated as effective or moderate in the treatment of primary lesions, 9 were also evaluated as effective or moderate in the treatment of metastatic lesions, while 10 were judged as poor in the treatment of metastatic lesions. In 12 subjects which were evaluated as poor in the treatment of primary lesions, 3 were judged as moderate in the effect of treatment of metastatic lesions, while 9 were judged as poor. It was proved that the correct evaluation of the primary prostatic tumor was required to perform adequate treatment for Stage D2 prostatic cancer. transrectal ultrasonotomography ; prostatic cancer (Stage D2) ; evaluation of treatment