Sonomorphological Abnormalities in Sudanese Children with Schistosoma Mansoni Infection: A Proposed Staging-System for Field Diagnosis of Periportal Fibrosis

Schistosomiasis mansoni in low transmission areas: abdominal ultrasound

“…However, these precocious lesions are the most important to be identified because are more prevalent among the population living in endemic areas. Furthermore, the early diagnosis could be useful for planning selective or mass chemotherapy in endemic locali-ties (Doehring-Schwedtfeger et al 1989, Abdel-Wahab et al 1990) preventing the evolution toward hepatosplenic schistosomiasis (Bina & Prata 1981, 1983.…”

Serum hyaluronan and collagen IV as non-invasive markers of liver fibrosis in patients from an endemic area for schistosomiasis mansoni: a field-based study in Brazil

“…Considered a simple, safe and low-cost method, after the advent of portable equipment, it has been of invaluable help in the screening of populations living in endemic areas and in field-based studies of the disease. Taken as a nearly ideal tool in the diagnosis and classification of schistosomiasis, it is now used as a surrogate for the gold-standard in the diagnosis of schistosomiasis-related liver fibrosis (Doehring-Schwerdtfeger et al 1989, Abdel-Wahab et al 1992, Richter et al 1992, Abdel-Wahab & Strickland 1993, pinto-Silva et al 1994, Richter 2000, Kariuki et al 2001, Cota et al 2006, Marinho et al 2006, Ruiz-Guevara et al 2007.…”

Relationship between circulating antigen level and morbidity in Schistosoma mansoni-infected children evaluated by ultrasonography.

“…[3][4][5] In the present study, disease staging by ultrasound showed a higher mean antigen level in children with hepatosplenic disease than in those with intestinal disease (P Ͻ 0.05). Furthermore, a correlation was observed between increasing severity of ultrasonographically classified disease and antigenemia (P Ͻ 0.01).…”

“…[3][4][5] Abdel-Wahab and others 6 have reported that ultrasonographic grading accurately reflects the hemodynamic changes and provides a good estimate of the clinical status of patients who have periportal fibrosis as a result of schistosomiasis mansoni. They recommended that it should replace clinical grading based upon the liver and spleen size detected by physical examination.…”