2008
DOI: 10.1016/j.aca.2008.03.062
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Sorbent preconcentration procedures coupled to capillary electrophoresis for environmental and biological applications

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Cited by 69 publications
(55 citation statements)
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References 108 publications
(194 reference statements)
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“…However, the research in this field is mainly centered in the manufacturing process, so the application of such microdevices is rather limited. In the coming years research in this field will focus on exploring the potential of chip-based SPE-CE for its application in the analysis of real samples (Puig et al, 2007(Puig et al, , 2008. SPE is the most attractive way of coupling extraction with CE and, especially, MCE, particularly as it can provide significant improvements in sensitivity without the use of electrokinetic injection (Puig et al, 2007(Puig et al, , 2008Bertoncini & Hennion, 2004).…”
Section: Extraction Techniquesmentioning
confidence: 99%
See 1 more Smart Citation
“…However, the research in this field is mainly centered in the manufacturing process, so the application of such microdevices is rather limited. In the coming years research in this field will focus on exploring the potential of chip-based SPE-CE for its application in the analysis of real samples (Puig et al, 2007(Puig et al, , 2008. SPE is the most attractive way of coupling extraction with CE and, especially, MCE, particularly as it can provide significant improvements in sensitivity without the use of electrokinetic injection (Puig et al, 2007(Puig et al, , 2008Bertoncini & Hennion, 2004).…”
Section: Extraction Techniquesmentioning
confidence: 99%
“…In the coming years research in this field will focus on exploring the potential of chip-based SPE-CE for its application in the analysis of real samples (Puig et al, 2007(Puig et al, , 2008. SPE is the most attractive way of coupling extraction with CE and, especially, MCE, particularly as it can provide significant improvements in sensitivity without the use of electrokinetic injection (Puig et al, 2007(Puig et al, , 2008Bertoncini & Hennion, 2004). A potential of the affinity extraction in a chip format for a comprehensive proteomic analysis was demonstrated by Slentz (Slentz et al, 2003).…”
Section: Extraction Techniquesmentioning
confidence: 99%
“…Nevertheless, 3D phases have some drawbacks. Packed beds of non-magnetic beads require frits to retain the beads and can lead to increased backpressure, air bubbles, longer analysis times, and irreproducible electroosmotic flows (EOFs) [9]. Monoliths overcome these problems, but their synthesis remains complex and requires a technical expertise [10].…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3] Among them, solid-phase extraction (SPE) coupled to CE is a very promising technique because low limits of detection (LODs) can be achieved due to the high sample volume that can be injected. [3][4][5][6][7][8] SPE can mainly be performed in four different setups: off-line, on-line, at-line and in-line. The latter three of these setups have been of particular interest due to an increasing trend towards fully automated analytical methods; among them, in-line coupling on SPE and CE is the most widely reported at present.…”
Section: Introductionmentioning
confidence: 99%