Sorting microparticles by orientation using wedged-fin and railed microfluidics

The inherent coupling of chemical and mechanical behavior in fluid-filled microchambers enables the fluid to autonomously perform work, which in turn can direct the self-organization of objects immersed in the solution. Using theory and simulations, we show that the combination of diffusioosmotic and buoyancy mechanisms produce independently controlled, respective fluid flows: one generated by confining surfaces and the other in the bulk of the solution. With both flows present, the fluid can autonomously join 2D, disconnected pieces to a chemically active, “sticky” base and then fold the resulting layer into regular 3D shapes (e.g. pyramids, tetrahedrons, and cubes). Here, the fluid itself performs the work of construction and thus, this process does not require extensive external machinery. If several sticky bases are localized on the bottom surface, the process can be parallelized, with the fluid simultaneously forming multiple structures of the same or different geometries. Hence, this approach can facilitate the relatively low-cost, mass production of 3D micron to millimeter-sized structures. Formed in an aqueous solution, the assembled structures could be compatible with biological environments, and thus, potentially useful in medical and biochemical applications.

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Sorting microparticles by orientation using wedged-fin and railed microfluidics

Cited by 3 publications

References 12 publications

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