Three‐dimensional (3D) structure‐reinforced flexible polymer composites have great potential as personal protective materials. These composites exhibit excellent mechanical properties and failure mechanisms than typical rigid composites because of the complex dynamic reaction processes caused by the 3D structure in response to impact. This paper comprehensively reviews the impact resistance mechanism of 3D structure‐reinforced flexible polymer composites by combining current results with relevant investigations. 3D woven fabric reinforcements and flexible matrix materials of flexible polymer composites systems are presented in this paper. The classification for 3D woven fabric reinforcements is reviewed, as well as the effect of reinforcement structures on the impact resistance of the flexible composites. Furthermore, several flexible matrix are introduced. Several external factors affecting the impact resistance of composites are then discussed. Finally, the impact damage mechanism of 3D structure‐reinforced flexible polymer composites is summarized and analyzed.