In the context of increasing online health misinformation, several new approaches have been deployed to reduce the spread and increase the quality of information consumed. This systematic review examines how source credibility labels and other nudging interventions impact online health information choices. PubMed, Embase, Scopus, and Web of Science were searched for studies that present empirical evidence on the impact of interventions designed to affect online health-information-seeking behavior. Results are mixed: some interventions, such as content labels identifying misinformation or icon arrays displaying information, proved capable of impacting behavior in a particular context. In contrast, other reviewed strategies around signaling the source’s credibility have failed to produce significant effects in the tested circumstances. The field of literature is not large enough to draw meaningful conclusions, suggesting that future research should explore how differences in design, method, application, and sources may affect the impact of these interventions and how they can be leveraged to combat the spread of online health misinformation.