The Nozoe Autograph Books contain entries from, literally, around the world of organic chemistry. Many of the inscriptions showed the poetic or even musical side of their signees. This Essay presents a diverse selection of the poetic entries of the autograph books, starting with a musical puzzle (see picture). This Essay and the interactive website that accompanies the Nozoe Autograph Book project are available free‐access for at least a three‐year period at http://www.tcr.wiley-vch.de/nozoe.