The information about COVID-19 prevalence, symptoms, and treatment among Indonesian college students has been limited. This study aims to discover the epidemiological characteristic and clinical phenomenon of COVID-19 infection among university students in Indonesia to provide valuable references for better future prevention. We surveyed 285 college students aged 18-28 between February and June 2022. An online form was used to gain information about the experience of COVID-19 infection, transmission, symptoms, treatments, and activity during infection since the pandemic began until 30th June 2022. Ninetyfive students contracted COVID-19, and almost half (49.5%) were infected in 2021. The most frequently reported source of infection was household transmission (33.3%), followed by public places (30.5%), campus (4.2%), and unknown (31.6%). The predominant symptoms included fever (76.8%), cough (63.1%), and loss of taste or smell (57.9%). Most students (77.9%) experienced mild symptoms, 9.5% without any symptoms, 10.5% were hospitalized, and 2.1% required Intensive Care Unit treatment. Almost all of them (88.4%) were isolated at home or in the hospital, and 50.5% had no restriction to following lectures and doing assignments. Around a third of students experienced COVID-19 during the pandemic. The most common symptoms are fever, cough, and loss of taste or smell. Most symptoms are mild, and almost half of the students actively attended online lectures.