spa typing of methicillin-resistant Staphylococcus aureus isolated from domestic animals and veterinary staff in the UK and Ireland

Abstract

Irrespective of geographical origin, MRSA isolated from equine and small animal hospitals generally clustered into two distinct clonal complexes, CC8 and CC22, respectively. The combined use of spa and PFGE typing allowed better discrimination than each method used individually, and provided useful information on MRSA transmission between animal and human individuals.

Methicillin-resistant Staphylococcus aureus in horses and horse personnel: An investigation of several outbreaks

“…The high prevalence of ST398 in pigs and veal calves in the Netherlands (de Neeling et al, 2007;Graveland et al, 2008) and the fact that horses are often kept on farms with other livestock and are sometimes treated by veterinarians who are also involved in the treatment of livestock are likely explanations for the increase of ST 398 in horses. MRSA ST8 of spa-type t064 have also been found in horses and staff at a veterinary hospital in Ireland (Moodley et al, 2006) and MRSA ST398 spa-type t011 have been found in horses and staff in a teaching hospital in Vienna (Cuny et al, 2008). The international travel and trade of horses may favour the dissemination of the MRSA.…”

Nosocomial Infections and their Surveillance in Veterinary Hospitals

“…After this MRSA has been isolated from various species like dogs (Pak et al, 1999), cats (Scott et al, 1988), sheep (Goni et al, 2004), horses (Seguin et al, 1999), pigs (Voss et al, 2005) and chickens (Lee, 2003). Methicillin-resistant Staphylococcus aureus (MRSA) is an important concern nowadays in pet animals for being a significant cause in nosocomial infections (Weese, 2008b; and also a threat of zoonoses to veterinary health care personnel (Loeffler et al, 2010;Burstiner et al, 2010) and horses may act as a reservoir of MRSA and serve as a source of infection to humans (Weese et al, 2005a (Enright et al, 2000), spa typing (Moodley et al, 2006). The data obtained through all these studies sturdily suggesting the bidirectional transmission of MRSA between companion animals and human .…”

Characterization of virulence and antibiotic profile and agr typing of Staphylococcus aureus from milk of subclinical mastitis bovine in State of Rio de Janeiro

“…The accessory gene regulator (agr) can regulate the expression of cell surface proteins and extracellular virulence factors (Moodley et al, 2006). agr (accessory gene regulator) locus is a quorum-sensing system that controls expression of a variety of genes involved in tissue colonization (e.g., surface proteins) and invasion (e.g., extracellular toxins).…”