The 5G, as a new source of telecommunication infrastructure technology, has attracted many stakeholders to promote the progress of its standards and the development of its technology industry. The 5G reinforces new technologies and delivers vehicles for everything services (V2X) to drivers and passengers. It also offers several advantages. On the other hand, due to pervasive network connectivity, there are significant trust, security, and privacy issues for vehicles this affects the overall performance of 5G V2X. This paper provides a comprehensive review; and particularly; an overview of the mobile communication system and introduces the Next Generation (NG). additionally, the paper concentrates on the fifthgeneration structure and its use cases. The 5G-V2X as a new field of communication requires more attention and focus, moreover, it aims to present the problems facing this new technology as well, and some future directions for research have been highlighted.