Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets
Benjamin R. Helmold,
Angela Ahrens,
Zachary Fitzgerald
et al.
Abstract:Developing effective and long-term treatment strategies for rare and complex neurodegenerative diseases is challenging. One of the major roadblocks is the extensive heterogeneity among patients. This hinders understanding the underlying disease- causing mechanisms and building solutions that have implications for a broad spectrum of patients. One potential solution is to develop personalized medicine approaches based on strategies that target the most prevalent cellular events that are perturbed in patients. E… Show more
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