Spathulenol as the most abundant component of essential oil of Moluccella aucheri (Boiss.) Scheen

Doorandishan, Mina; Gholami, Morteza; Ebrahimi, Pouneh; Jassbi, Amir Reza

doi:10.37929/nveo.817562

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…(+)Spathulenol is used in the production of environmentally friendly insecticides against cereal pests. [40] (+)Spathulenol also has anticholinesterase, [41,42] antinociceptive, anti-hyperalgesic, [42,43] anti-micobacterial, [42,44,45] antioxidant, anti-proliferative, anti-oedematogenic, [42,45] cytotoxicity, [42,46] and is used as a chemotherapy adjuvant for MDR cancer. [42,47] While cis-lanceol was represented in S. lappa and L. sinensis (0.46 % and 0.24 %, respectively).…”

Section: Chemical Composition Of the Essential Oilmentioning

confidence: 99%

Secondary Metabolites Generated from Saussurea lappa and Ligusticum sinensis Essential Oils by Microwave‐Assisted Hydrodistillation: in Silico Molecular Docking and in Vitro Antibacterial Efficacy

Abd El‐Razek,

Saleh,

Abdel‐Halim

et al. 2023

Chemistry & Biodiversity

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In the current study, both the essential oil composition and biological activity of Saussurea lappa and Ligusticum sinensis were investigated by means of microwave‐assisted hydrodistillation (MAHD) and characterized by Gas chromatography/mass spectrometry (GC/MS), whereas the antimicrobial efficiency of MAHD essential oils was examined against four pathogens: Staphylococcus aureus, Escherichia coli, Aspergillus niger, and Candida albicans responsible for microbial infections. The goal was to spot synergy and a favorable method that gives essential oils to possibly use as alternatives to common antimicrobial agents for the treatment of bacterial infections using a microdilution assay. S. lappa's 21 compounds were characterized by MAHD extraction. Sesquiterpene lactones (39.7 % MAHD) represented the major components, followed by sesquiterpene dialdehyde (25.50 % MAHD), while L. sinensis's 14 compounds were identified by MAHD extraction. Tetrahydroisobenzofurans (72.94 % MAHD) was the predominant compound class. S. lappa essential oil collection showed the strongest antimicrobial activity with MIC values of 16 μg/ml against all pathogens tested, while L. sinensis showed strong antibacterial activity and moderate antifungal activity with MIC values of 32 μg/ml and 500 μg/ml, respectively. The principal components of both oils, (velleral, eremanthin and neocnidilide), were docked into the bacterial histidine kinase (HK) and the fungal heat shock protein 90 (Hsp90).

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Section: Chemical Composition Of the Essential Oilmentioning

confidence: 99%

Secondary Metabolites Generated from Saussurea lappa and Ligusticum sinensis Essential Oils by Microwave‐Assisted Hydrodistillation: in Silico Molecular Docking and in Vitro Antibacterial Efficacy

Abd El‐Razek,

Saleh,

Abdel‐Halim

et al. 2023

Chemistry & Biodiversity

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“…It also plays significant roles in pathophysiologic processes like oxidative stress, thymidine incorporation in to DNA and inflammation [37]. Spathulenol (another abundant compound in the leaves EO of C. adenocaule), is a tricyclic sesquiterpene with 5,10-cycloaromadendrane skeleton [44]. Literature surveys revealed that spathulenol possess significant biological applications such as antihyperalgesic, antioxidant, anticholinesterase, antibacterial, antiproliferative, antiinflammatory, antioedematogenic, chemotherapy of MDR cancer and cytotoxicity [39].…”

Section: Antibacterial Activitiesmentioning

confidence: 99%

Chemical composition, antibacterial and antioxidant activities of essential oils from Ccyphostemma adenocaule and Ziziphus spinachristi

Gebrehiwot,

Dekebo,

Shenkute

et al. 2023

Bull. Chem. Soc. Eth.

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In the present work, the chemical composition, antibacterial and antioxidant potencies of essential oils (EOs) extracted from the leaves and roots of Cyphostemma adenocaule and Ziziphus spinachristi were evaluated. Hydrodistillation was used to extract the EOs and the chemical compositions were analyzed by GC-MS. The antibacterial activity of the EOs were evaluated against four bacterial strains by agar disc diffusion method. Moreover, the antioxidant properties were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay method. Perillyl alcohol (13.08%) and phytone (12.64%) were the major compounds detected in the leaves and roots of Cyphostemma adenocaule respectively. Whereas, nootkatone was the principal compound detected in the leaves (30.12%) and roots (26.52%) of Ziziphus spinachristi. The antibacterial activity results showed that, the EOs of Cyphostemma adenocaule and Ziziphus spinachristi displayed the highest inhibition zones against Streptococcus pyogenes (13.67 ± 0.34 and 12.67 ± 0.10 mm respectively) at 10 mg/mL. The antioxidant activity of the EOs were also promising, and the strongest IC50 value (4.15 µg/mL) was calculated for Ziziphus spinachristi (leaves). Thus, the antibacterial and antioxidant properties of the EOs enlighten the use of these plants for the aforementioned activities and as a common ingredients in cosmetic applications. KEY WORDS: Essential oils, Antibacterial activity, Antioxidant activity, Cyphostemma adenocaule, Ziziphus Bull. Chem. Soc. Ethiop. 2024, 38(1), 167-186. DOI: https://dx.doi.org/10.4314/bcse.v38i1.13

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The chemical composition and biological activities of essential oil from the aerial parts of Eryngium maritimum L. (Apiaceae)

Elkıran

Avşar

Veyisoglu

et al. 2023

Journal of Essential Oil Bearing Plants

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Spathulenol as the most abundant component of essential oil of Moluccella aucheri (Boiss.) Scheen

Cited by 3 publications

References 16 publications

Secondary Metabolites Generated from Saussurea lappa and Ligusticum sinensis Essential Oils by Microwave‐Assisted Hydrodistillation: in Silico Molecular Docking and in Vitro Antibacterial Efficacy

Secondary Metabolites Generated from Saussurea lappa and Ligusticum sinensis Essential Oils by Microwave‐Assisted Hydrodistillation: in Silico Molecular Docking and in Vitro Antibacterial Efficacy

Chemical composition, antibacterial and antioxidant activities of essential oils from Ccyphostemma adenocaule and Ziziphus spinachristi

The chemical composition and biological activities of essential oil from the aerial parts of Eryngium maritimum L. (Apiaceae)

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