Spatial and temporal trends in alcohol consumption in Belgian cities: A wastewater-based approach

Boogaerts, Tim; Covaci, Adrian; Kinyua, Juliet; Neels, Hugo; Nuijs, Alexander L.N. van

doi:10.1016/j.drugalcdep.2016.01.002

Cited by 67 publications

(46 citation statements)

References 19 publications

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“…The potential rapid degradation of EtS and EtG, especially EtG (Figures a and b), in the sewer system may limit their applicability as biomarkers for the estimation of alcohol consumption in the population, although both of them are still currently used in urinalysis to detect alcohol consumption in individuals . With a complete loss after only 2 hours in both RM and GS reactors, EtG is not recommended to be used to estimate alcohol consumption in WBE studies, which supports the practice in all WBE studies related to alcohol after the initial assessment of Reid et al (Table ). In general, as found in this and other studies, glucuronide compounds are very quickly transformed in wastewater, and hence are not suitable to be used as biomarkers in WBE.…”

Section: Discussionmentioning

confidence: 87%

Potential impact of the sewer system on the applicability of alcohol and tobacco biomarkers in wastewater‐based epidemiology

Banks

Lai

Mueller

et al. 2017

Drug Testing and Analysis

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Understanding the actual consumption of alcohol and tobacco in the population is important for forming public health policy. For this purpose, wastewater-based epidemiology has been applied as a complementary method to estimate the overall alcohol and tobacco consumption in different communities. However, the stability of their consumption biomarkers - ethyl sulfate, ethyl glucuronide, cotinine, and trans-3'-hydroxycotinine - in the sewer system has not yet been assessed. This study aimed to conduct such assessment using sewer reactors mimicking conditions of rising main, gravity sewer, and wastewater alone, over a 12-hour period. The results show that cotinine and trans-3'-hydroxycotinine are relatively stable under all sewer conditions while ethyl sulfate was only stable in wastewater alone and gradually degraded in rising main and gravity sewer conditions. Ethyl glucuronide quickly degraded in all reactors. These findings suggest that cotinine and trans-3'-hydroxycotinine are good biomarkers to estimate tobacco consumption; ethyl sulfate may be used as a biomarker to estimate alcohol consumption, but its in-sewer loss should be accounted for in the calculation of consumption estimates. Ethyl glucuronide, and probably most of glucuronide compounds, are not suitable biomarkers to be used in wastewater-based epidemiology due to their in-sewer instability.

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Section: Discussionmentioning

confidence: 87%

Potential impact of the sewer system on the applicability of alcohol and tobacco biomarkers in wastewater‐based epidemiology

Banks

Lai

Mueller

et al. 2017

Drug Testing and Analysis

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“…The successes of WBE that have been demonstrated on global scales have given rise to discussions on future outlooks for the technique (Choi et al, 2018;Daughton, 2018;Kasprzyk-Hordern et al, 2014;Thomas and Reid, 2011). Initially, work was entirely focused upon illicit drug usage, including heroin, cocaine and methamphetamines (Boleda et al, 2007;Castiglioni et al, 2006;Kasprzyk-Hordern et al, 2008;Zuccato et al, 2008) but have since expanded to include a diverse range of other endogenous biomarkers, varying from ones linked to lifestyle choices such as alcohol consumption (Boogaerts et al, 2016;Reid et al, 2011;Rodríguez-Álvarez et al, 2014a), tobacco (Castiglioni et al, 2015;Lai et al, 2017;Rodríguez-Álvarez et al, 2014b;Ben J. Tscharke et al, 2016) and psychoactive substances (Kinyua et al, 2015;Mardal and Meyer, 2014;Reid et al, 2014). Others have investigated general health through oxidative stress markers (Ryu et al, 2016(Ryu et al, , 2015.…”

Section: Water Fingerprinting Via Wastewater-based Epidemiology -A Nementioning

confidence: 99%

Future perspectives of wastewater-based epidemiology: Monitoring infectious disease spread and resistance to the community level

Sims

Kasprzyk-Hordern

2020

Environment International

518

348

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Infectious diseases are acknowledged as one of the most critical threats to global public health today. Climate change, unprecedented population growth with accelerated rates of antimicrobial resistance, have resulted in both the emergence of novel pathogenic organisms and the re-emergence of infections that were once controlled. The consequences have led to an increased vulnerability to infectious diseases globally. The ability to rapidly monitor the spread of diseases is key for prevention, intervention and control, however several limitations exist for current surveillance systems and the capacity to cope with the rapid population growth and environmental changes. Wastewater-Based Epidemiology (WBE) is a new epidemiology tool that has potential to act as a complementary approach for current infectious disease surveillance systems and an early warning system for disease outbreaks. WBE postulates that through the analysis of population pooled wastewater, infectious disease and resistance spread, the emergence of new disease outbreak to the community level can be monitored comprehensively and in real-time. This manuscript provides critical overview of current infectious disease surveillance status, as well as it introduces WBE and its recent advancements. It also provides recommendations for further development required for WBE application as an effective tool for infectious disease surveillance.

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“…Measures of the ethanol metabolite (ethyl sulphate) were used to estimate alcohol consumption for the first time in the Norwegian population , and a recent WBE study reported spatial patterns of alcohol consumption across 20 cities in 11 countries . Other studies have been conducted in Belgium, Greece, Italy and Spain .…”

Section: Introductionmentioning

confidence: 99%

Measuring spatial and temporal trends of nicotine and alcohol consumption in Australia using wastewater‐based epidemiology

et al. 2018

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Spatial and temporal trends in alcohol consumption in Belgian cities: A wastewater-based approach

Abstract: This is the largest wastewater-based epidemiology study monitoring alcohol consumption to date, demonstrating that objective and quick information on spatio-temporal trends in alcohol consumption on a local and (inter)national scale can be obtained.

Cited by 67 publications

References 19 publications

Potential impact of the sewer system on the applicability of alcohol and tobacco biomarkers in wastewater‐based epidemiology

Potential impact of the sewer system on the applicability of alcohol and tobacco biomarkers in wastewater‐based epidemiology

Future perspectives of wastewater-based epidemiology: Monitoring infectious disease spread and resistance to the community level

Measuring spatial and temporal trends of nicotine and alcohol consumption in Australia using wastewater‐based epidemiology

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