Reference crop evapotranspiration (ETo) is an important component of the hydrological cycle that is used for water resource planning, irrigation, and agricultural management, as well as in other hydrological processes. The aim of this study was to estimate the ETo based on limited meteorological data using an artificial neural network (ANN) method. The daily data of minimum temperature (Tmin), maximum temperature (Tmax), mean temperature (Tmean), solar radiation (SR), humidity (H), wind speed (WS), sunshine hours (Ssh), maximum global radiation (gradmax), minimum global radiation (gradmin), day length, and ETo data were obtained over the long-term period from 1969 to 2019. The analysed data were divided into two parts from 1969 to 2007 and from 2008 to 2019 for model training and testing, respectively. The optimal ANN for forecasting ETo included Tmax, Tmin, H, and SR at hidden layers (4, 3); gradmin, SR, and WS at (6, 4); SR, day length, Ssh, and Tmean at (3, 2); all collected parameters at hidden layer (5, 4). The results showed different alternative methods for estimation of ETo in case of a lack of climate data with high performance. Models using ANN can help promote the decision-making for water managers, designers, and development planners.