I. INTRODUCTION R ESEARCH in large-scale networking systems has been shaped and will continue to be guided by specific characteristics of applications and the underlying platforms and infrastructures. On the one hand, applications are growing at an accelerated pace, which is fundamentally unpredictable in both breadth and depth. On the other hand, the underlying networking has been the focus of a huge transformation enabled by new models resulting from virtualization and cloud computing. This has led to a number of novel architectures supported by emerging technologies such as Software-Defined Networking (SDN), Network Function Virtualization (NFV), and more recently, edge cloud and fog networking, or network slicing [1], [2]. This evolution towards enhanced design opportunities along with increasing complexity in networking and its applications has fueled the need for improved network automation in agile infrastructures. At the same time, their complexity has dramatically increased. The networking dynamics have had the effect of making it even more important and challenging to design scalable network measurement and analysis techniques and associated tools. Critical applications such as resource allocation, network monitoring, security enforcement, or dynamic network management require real-time mechanisms for online analysis as well as efficient techniques for offline deep analysis of massive historical data.