Solid wastes are substances by the owner of those properties. The increasing quantity of solid waste makes its management complicated issues. The main objective was to determine health impacts of solid waste management problems. A cross-sectional study design was selected during the data collection process. The sampling technic was randomly and systematically selected houses with a sample size of 423. The data collection tools were checklists, open and closed-ended questionnaires. Collected data entered into EPI data 4.6 and transported to Minitab 20.3 software. Both the chi-square and ANOVA tests were selected for statistical analysis purposes. The response of health impact assessment questions were 207 (49.5%) respiratory diseases, 76 (18.2%) asthmatic (bronchitis) cases, 66 (15.8%) diarrheal diseases, 62 (14.8%) protozoan diseases, and 7 (1.7% ) develop cancer cases. The responses to the environmental pollution responses were 143 (34.2%) water pollution, 132 (31.6%) air pollution, 56 (13.4%) soil pollution, and 87 (20.8%) global environmental problems. ANOVA test obtained strong relations with age groups, education, costs, and health impacts. The Chi-square test found strong associations exist between gender and solid waste sorting process. Therefore, improper solid waste management systems were found in diarrhoeal and parasitic disease episodes during the study of health problems in Asella, Ethiopia.