Spatial Functional Distribution in the Corticospinal Tract at the Corona Radiata: A Three-dimensional Anisotropy Contrast Study.

Inoue, Takashi; Shimizu, Hiroaki; Yoshimoto, Takashi; Kabasawa, Hiroyuki

doi:10.2176/nmc.41.293

Cited by 13 publications

(9 citation statements)

References 43 publications

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“…DW or DT imaging in the acute phase have the potential to predict motor function outcome in patients with ischemic or hemorrhagic diseases [13,14,15,21]. Decreased FA values in the remote pyramidal tract after stroke are associated with Wallerian degeneration.…”

Section: Discussionmentioning

confidence: 99%

Prediction of Motor Function Outcome after Intracerebral Hemorrhage Using Fractional Anisotropy Calculated from Diffusion Tensor Imaging

Kuzu¹,

Inoue

Kanbara

et al. 2012

Cerebrovasc Dis

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Background: The efficacy of surgical evacuation in patients with intracerebral hemorrhage (ICH) remains unclear for recovery of motor function. The relationship between improvement of motor function outcome and sequential change of fractional anisotropy (FA) values was investigated in patients with ICH, to explore whether motor function outcome can be predicted in the early phase. Indication of the surgical hematoma evacuation was also considered. Methods: This prospective study included 23 patients with ICH. All patients underwent diffusion tensor imaging to measure the FA value five times: within 3 days, day 14, day 30, day 60, and day 90 after the onset. The regions of interest were determined on the b = 0 step of the echo planar imaging scans in the bilateral cerebral peduncles and were automatically transferred onto the FA images. The FA value was then calculated for each patient. Patients were divided into good and poor recovery groups according to the motor function outcome on day 90. Results: The mean FA value of the poor recovery group gradually decreased until day 90, but remained unchanged in the good recovery group. The mean FA value on day 3 was significantly higher (p < 0.001) in the good recovery group (0.745 ± 0.0073) than in the poor recovery group (0.682 ± 0.0090). Receiver operating characteristic curve analysis showed that the FA value on day 3 could predict motor function outcome with a sensitivity of 100% and a specificity of 77.8% at an FA value of 0.7 on day 3. Conclusion: The main finding of this study was that the FA values of the cerebral peduncle on the pathological side in patients with ICH on day 3 could predict the motor function outcome on day 90.

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Section: Discussionmentioning

confidence: 99%

Prediction of Motor Function Outcome after Intracerebral Hemorrhage Using Fractional Anisotropy Calculated from Diffusion Tensor Imaging

Kuzu¹,

Inoue

Kanbara

et al. 2012

Cerebrovasc Dis

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“…Previous studies have used various methods to locate the CST in the human brain [4,6,12,[16][17][18][19][20][21]24,28,34,35,[39][40][41]. In earlier studies, invasive methods such as dissection of the brain or direct electrical stimulation were used [6,12,16,17,28,35], however, the development of radiologic techniques such as brain CT and MRI enabled more recent studies to be conducted using noninvasive methods [18][19][20]39,40].…”

Section: The Evaluation Methods Used To Locate the Cstmentioning

confidence: 99%

“…There have been several studies conducted that have described the location of the CST in the CR [21,26,37,38,41]. In 1996, Tohgi et al measured the relative distance to the center of an infarct from the anterior pole to the posterior pole of the lateral ventricle in patients with CR infarct using brain CT.…”

Section: The Location Of the Cst At The Corona Radiatamentioning

confidence: 99%

A review of corticospinal tract location at corona radiata and posterior limb of the internal capsule in human brain

Jang

2009

NRE

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The corticospinal tract (CST) is the most important motor pathway in the human brain, therefore, the accurate estimation of the CST state following brain injury would enable us to predict the motor outcome or enable accurate surgical planning. The corona radiata (CR) and the posterior limb of the internal capsule (PL) are important locations because they are related to poor motor outcome. In this study, we reviewed the available literature regarding the location of the CST at the CR and PL in the human brain. The results of this review indicate that the CST is located in the posterior portion of the CR and PL. However, a direct comparison of the results of previous studies would be impossible because many of the previous studies did not define the exact boundary or analytic standards used to locate the CR or PL. Therefore, further complementary studies that define these in detail are warranted.

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“…Clinical recovery observations and brain MRI and DTT findings indicated that the stroke patients examined during the present study were able to walk without a functioning lateral CST of the affected hemisphere. These stroke patients initially showed complete hemiplegia due to a lesion in the corona radiata, the known pathway of CST (posterior portion of the corona radiata) [8][9][10]. The motor function of affected legs was slowly recovered over 3 months or more, to the extent of being able to overcome gravity.…”

Section: Discussionmentioning

confidence: 99%

“…We recruited 10 consecutive stroke patients from among stroke patients admitted for rehabilitation over an 18-month period, according to the following selection criteria: (1) a duration of more than 6 months since stroke onset; (2) an ability to walk on even ground without an assisting device; (3) complete paralysis of the affected upper and lower extremities at the time of stroke onset and a motor recovery time of at least 3 months enabling movement of the affected hip and knee extensor muscles against gravity; (4) brain MRI evidence of CST pathway injury at the corona radiata [8][9][10], as confirmed by a neuroradiologist; and (5) the CST confined within the brainstem or absent, even if the fractional anisotropy (FA) value was set as low as 0.1, owing to severe Wallerian degeneration.…”

Section: Methodsmentioning

confidence: 99%

Can stroke patients walk after complete lateral corticospinal tract injury of the affected hemisphere?

Ahn

Kim³

et al. 2006

NeuroReport

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The lateral corticospinal tract is the major motor pathway in humans. The role of this tract on walking, however, is uncertain. The development of di¡usion tensor tractography enables corticospinal tract status to be visualized at the subcortical level. In the present study, we undertook to demonstrate that some stroke patients can walk despite complete lateral corticospinal tract injury. Ten stroke patients who were able to walk with evidence of complete unilateral lateral corticospinal tract injury, as determined by clinical course, brain magnetic resonance imaging, and di¡usion tensor tractography, were recruited. We conclude that some stroke patients can walk despite complete lateral corticospinal tract injury of the a¡ected hemisphere. NeuroReport17:987^990

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Spatial Functional Distribution in the Corticospinal Tract at the Corona Radiata: A Three-dimensional Anisotropy Contrast Study.

Cited by 13 publications

References 43 publications

Prediction of Motor Function Outcome after Intracerebral Hemorrhage Using Fractional Anisotropy Calculated from Diffusion Tensor Imaging

Prediction of Motor Function Outcome after Intracerebral Hemorrhage Using Fractional Anisotropy Calculated from Diffusion Tensor Imaging

A review of corticospinal tract location at corona radiata and posterior limb of the internal capsule in human brain

Can stroke patients walk after complete lateral corticospinal tract injury of the affected hemisphere?

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