Centrifugal spinning process is a novel method used to produce nanofibers. In this process, we focus on the temporal and spatial instability of slender non-Newtonian jets falling under gravity in the presence of centrifugal forces and surfactants. The effects of the surfactants on the trajectory of non-Newtonian jets in the centrifugal spinning have been shown using asymptotic and numerical approaches. Furthermore, the results obtained from the linear theory have been used to estimate the break-up lengths and droplet sizes of this study. Our results also show that surfactants can provide a possibility of further manipulating of the break-up and main droplets.