Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure

Akbarnejad, Zeinab; Esmaeilpour, Khadijeh; Shabani, Mohammad; Asadi-Shekaari, Majid; Goraghani, Monavvar Saeedi; Ahmadi-Zeidabadi, Meysam

doi:10.1080/00207454.2017.1411353

Cited by 28 publications

(11 citation statements)

References 28 publications

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“…La estimulación con el CEM indujo a una mejoría en la prueba de giros inducidos, a pesar de que no cambió el número de neuronas dopaminérgicas en la SNc. Esto puede explicarse por otros mecanismos, como el aumento en los factores neurotróficos y la reducción del nivel oxidante, ambos como consecuencia de la estimulación magnética reportada para modelos animales de la enfermedad de Alzheimer (Akbarnejad et al, 2018) o de Huntington (Tasset et al, 2012).…”

Section: Discussionunclassified

Tratamiento a largo plazo con campos electromagnéticos en un modelo animal de la enfermedad de Parkinson

Medina-Salazar¹,

Moreno-Fitz²,

Jiménez³

et al. 2021

TIP RECQB

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La enfermedad de Parkinson (EP) es un padecimiento neurodegenerativo que afecta las neuronas de la sustancia negra pars compacta (SNc), provocando alteraciones motoras y no motoras. En la actualidad para el tratamiento de pacientes con EP se aplica la Estimulación con Campos Electromagnéticos (CEM), observándose cierta mejoría clínica. Sin embargo, su mecanismo terapéutico subyacente sigue sin ser dilucidado. Los estudios en modelos animales de la EP se han realizado por periodos cortos de estimulación con CEM. Por lo tanto, el objetivo del presente estudio fue investigar los cambios en el comportamiento motor de ratas Wistar con hemiparkinson, tratadas con CEM de 60 Hz, 2 horas diariamente durante 6 meses. Mensualmente se realizaron evaluaciones de conducta: rotación inducida por apomorfina, campo abierto, laberinto elevado en cruz y barra de equilibrio. Al finalizar el tratamiento se contó el número de neuronas dopaminérgicas en la SNc y se estimó su grado de pérdida. Los animales lesionados que recibieron CEM tuvieron una ganancia de peso similar a los animales control. El tratamiento redujo la conducta de giro y mejoró el equilibrio, sin cambios significativos en la sobrevida de las neuronas dopaminérgicas de la SNc. Estos resultados apoyan el uso de los CEM de 60 Hz como una terapia complementaria que puedan ayudar a mejorar los síntomas motores de la enfermedad.

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Section: Discussionunclassified

Tratamiento a largo plazo con campos electromagnéticos en un modelo animal de la enfermedad de Parkinson

Medina-Salazar¹,

Moreno-Fitz²,

Jiménez³

et al. 2021

TIP RECQB

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“…[42] There are several studies shoes LFMF benefits in killing viruses as well as enhancing the immune system functions. [43][44][45][46][47][48][49][50] In 1980s, Robach et al [56] and Cerf [57] demonstrated that ultrasonic energy can be absorbed by viruses and terminated them when use appropriately. This means viruses are sensitive to Ultrasonic energy.…”

Section: Discussionmentioning

confidence: 99%

INTRODUCING COVID-19 AS AN EVOLUTIONARY METABOLIC INFECIOUS DISEASE (EMID) The Prime Cause and Representing Alternative Treatment for COVID-19 (SARS-CoV-2)

Niknamian¹

2021

Preprint

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Background: Coronaviruses are a group of related viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that can range from mild to lethal. Mild illnesses include some cases of the common cold, while more lethal varieties can cause SARS, MERS, and COVID-19. The outbreak was identified in Wuhan, China, in December 2019, declared to be a Public Health Emergency of International Concern on 30 January 2020, and recognized as a pandemic on 11 March 2020. Introduction: Coronaviruses are the subfamily Orthocoronavirinae, within the family of Coronaviridae, order Nidovirales, and realm Riboviria. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses is approximately from 26 to 32 kilobases. Coronaviruses were first discovered in the 1930s and Human coronaviruses were discovered in the 1960s. The earliest ones studied were from human patients with the common cold, which were later named human coronavirus 229E and human coronavirus OC43. Other human coronaviruses have since been identified, including SARS-CoV in 2003, HCoV NL63 in 2004, HKU1 in 2005, MERS-CoV in 2012, and SARS-CoV-2 in 2019. Most of these have involved serious respiratory tract infections. Discussions and Results: Based on our multidisciplinary research, we have found the major cause and some treatments methods for fighting this powerful pathogen. The prime cause of COVID-19 is pushing the mitochondrial to lose MMP. A loss of the MMP by any mechanism leads to functional and structural collapse of the mitochondria and cell death. Mitophagy plays an important role in maintaining mitochondrial homeostasis, but can also eliminate healthy mitochondria in cases such as cell starvation, viral invasion, and erythroid cell differentiation. The mitochondrial fusion and fission are highly dynamic. Viruses specially COVID-19, interfere with these processes to distort mitochondrial dynamic to facilitate their proliferation. Thus, interfering with these processes promotes the interference of different cellular signaling pathways. The severe acute respiratory syndrome coronavirus (SARS-CoV) escapes the innate immune response by translocating its ORF-9b to mitochondria and promotes proteosomal degradation of dynamin-like protein (Drp1) leading to mitochondrial fission. We also researched on Ultrasonic Energy to destroy the virus which lead to positive results but it needs more future research. The most destructive way of viruses is to enhance Reactive Oxygen Species (ROS) and free radicals in human contaminated cell which cause inflammation in a host cell. ELF-EMF convert free radicals 2 into less active molecules and eliminate them into two pathways which has been discussed in the discussion part. Using ELF-EMF affects the second pathway that relies on the activity of the catalase and superoxide dismutase enzymes which is the most effective pathway. For the best result of treatment, is the use of low-frequency magnetic fields (LFMF) plus EMF-ELF which penetrate into deeper tissues, cells and mitochondria. We also have gone through many researches since 1920 and found if we emit the frequency as the same frequency of COVID-19, can cause resonance in the virus and destroy it. So we measured the SARS-CoV-2 frequency by Cyclotron and calculated the frequency of the virus is 30 KHz-500 KHz. Conclusion: COVID-19 (SARS-CoV-2) is one of the most complex virus which has been discovered since 2020. Until today, there has been no Antiviral Drug which can be useful in the treatment of this infectious disease has been discovered till today. COVID-19 genomic sequence containing SARS-CoV, MERS-CoV and Influenza A. Therefore; there is a high possibility of continuing COVID-19 even in summer. To gain the best result in treatment, we should use low-frequency magnetic fields (LFMF) plus EMF which penetrate into deeper tissues, cells and mitochondria in order to reduce ROS and Inflammation. In order to destroy SARS-CoV-2 virus in environment and also in infected individuals, we should use ELF-EMF plus LFMF. We also have gone through many researches since 1920 and found if we emit the frequency as the same frequency of COVID-19, it can cause resonance in the virus and destroy it. So we measured the SARS-CoV-2 frequency by Cyclotron and calculated the frequency of the virus that id is 30 KHz-500 KHz. The differences in the frequencies is due to the size of the virus which is from 26 to 32 Kilobases.

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“…Therefore; in order to gain the best results, is to use Low Frequency Magnetic Fields (LFMF) which had been tested and demonstrated by Royal Raymond Rife in 1920 [42]. There are several studies shoes LFMF benefits in killing viruses as well as enhancing the immune system functions [43][44][45][46][47][48][49][50] In 1980s, Robach et al [56] and Cerf [57] demonstrated that ultrasonic energy can be absorbed by viruses and terminated them when use appropriately. This means viruses are sensitive to Ultrasonic energy.…”

Section: Discussionmentioning

confidence: 99%

Introducing covid-19 as an evolutionary metabolic infectious disease (EMID). The prime cause and representing alternative treatment for Covid-19 (SARS-cov-2)

Niknamian¹

2020

Clin Case Rep Rev

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Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure

Abstract: Our results showed that application of ELF-MF not only has improving effect on different cognitive disorder signs of AD animals, but also disrupts the processes of AD rat model formation.

Cited by 28 publications

References 28 publications

Tratamiento a largo plazo con campos electromagnéticos en un modelo animal de la enfermedad de Parkinson

Tratamiento a largo plazo con campos electromagnéticos en un modelo animal de la enfermedad de Parkinson

INTRODUCING COVID-19 AS AN EVOLUTIONARY METABOLIC INFECIOUS DISEASE (EMID) The Prime Cause and Representing Alternative Treatment for COVID-19 (SARS-CoV-2)

Introducing covid-19 as an evolutionary metabolic infectious disease (EMID). The prime cause and representing alternative treatment for Covid-19 (SARS-cov-2)

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