The Willamette Valley, bounded to the west by the Coast Range and to the east by the Cascade Mountains, is the largest river valley completely confined to Oregon. The fertile valley soils combined with a temperate, marine climate create ideal agronomic conditions for seed production. Historically, seed cropping systems in the Willamette Valley have focused on the production of grass and forage seeds. In addition to growing over two-thirds of the nation’s cool-season grass seed, cropping systems in the Willamette Valley include a diverse rotation of over 250 commodities for forage, seed, food, and cover cropping applications. Tracking the sequence of crop rotations that are grown in the Willamette Valley is paramount to answering a broad spectrum of agronomic, environmental, and economical questions. Landsat imagery covering approximately 25,303 km2 were used to identify agricultural crops in production from 2004 to 2017. The agricultural crops were distinguished by classifying images primarily acquired by three platforms: Landsat 5 (2003–2013), Landsat 7 (2003–2017), and Landsat 8 (2013–2017). Before conducting maximum likelihood remote sensing classification, the images acquired by the Landsat 7 were pre-processed to reduce the impact of the scan line corrector failure. The corrected images were subsequently used to classify 35 different land-use classes and 137 unique two-year-long sequences of 57 classes of non-urban and non-forested land-use categories from 2004 through 2014. Our final data product uses new and previously published results to classify the western Oregon landscape into 61 different land use classes, including four majority-rule-over-time super-classes and 57 regular classes of annually disturbed agricultural crops (19 classes), perennial crops (20 classes), forests (13 classes), and urban developments (5 classes). These publicly available data can be used to inform and support environmental and agricultural land-use studies.