Daily actual evapotranspiration (AET) and seasonal AET values are of great practical importance in the management of regional water resources and hydrological modelling. Remotely sensed AET models and Landsat satellite images have been used widely in producing AET estimates at the field scale. However, the lack of validation at a high spatial frequency under different soil water conditions and vegetation coverages limits their operational applications. To assess the accuracies of remote sensing‐based AET in an oasis‐desert region, a total of 59 local‐scale daily AET time series, simulated using HYDRUS‐1D calibrated with soil moisture profiles, were used as ground truth values. Of 59 sampling sites, 31 sites were located in the oasis subarea and 28 sites were located in the desert subarea. Additionally, the locally validated mapping evapotranspiration at high resolution with internalized calibration surface energy balance model was employed to estimate instantaneous AET values in the area containing all 59 of the sampling sites using seven Landsat subimages acquired from June 5 to August 24 in 2011. Daily AET was obtained using extrapolation and interpolation methods with the instantaneous AET maps. Compared against HYDRUS‐1D, the remote sensing‐based method produced reasonably similar daily AET values for the oasis sites, while no correlation was observed for daily AET estimated using these two methods for the desert sites. Nevertheless, a reasonable monthly AET could be estimated. The correlation analysis between HYDRUS‐1D‐simulated and remote sensing‐estimated monthly AET values showed relative root‐mean‐square error values of 15.1%, 12.1%, and 12.3% for June, July, and August, respectively. The root mean square error of the summer AET was 10.0%. Overall, remotely sensed models can provide reasonable monthly and seasonal AET estimates based on periodic snapshots from Landsat images in this arid oasis‐desert region.