Spatial Transcriptomics Reveals Alterations in Perivascular Macrophage Lipid Metabolism: Insights into the onset of Wooden Breast Myopathy in Broiler Chickens
Ziqing Wang,
Paul Khondowe,
Erin Brannick
et al.
Abstract:This study aims to use spatial transcriptomics to characterize the cell-type-specific expression profile associated with the microscopic features observed in Wooden Breast myopathy. 1 cm3muscle sample was dissected from the cranial part of the right pectoralis major muscle from three randomly sampled broiler chickens at 23 days post-hatch and processed with Visium Spatial Gene Expression kits (10X Genomics), followed by high-resolution imaging and sequencing on the Illumina Nextseq 2000 system. WB classificati… Show more
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