Special Issue “Anti-Oxidant and Anti-Inflammatory Properties of Natural Compounds”

Merah, Othmane

doi:10.3390/cosmetics10030080

Cosmetics

2023

DOI: 10.3390/cosmetics10030080

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Special Issue “Anti-Oxidant and Anti-Inflammatory Properties of Natural Compounds”

Othmane Merah

Abstract: Throughout history, humans have utilized plants as conscious or unconscious sources of molecules for food, health and well-being [...]

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2024

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Chemical Profile and Antioxidant and Tyrosinase Inhibitory Activity of Chamaemelum nobile L. Green Extracts

Polcaro,

Cerulli,

Montella

et al. 2024

Cosmetics

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The request for skin-whitening agents and bioactive principles able to control hyperpigmentation disorders is continuously growing. Chamomile (Matricaria chamomilla) is used as a remedy for skin diseases, but little is known about the ability of Roman chamomile (Chamaemelum nobile) to act as a skin-whitening agent. With the aim to investigate antioxidant and lightening potential, fresh aerial parts of C. nobile were extracted by maceration, ultrasound-assisted extraction, and solid–liquid dynamic (SLDE-Naviglio) extraction using EtOH/H2O mixtures. Moreover, 32 metabolites (flavonoids, sesquiterpenoids, amides, and polar fatty acids) were identified by liquid chromatography/mass spectrometry. Principal component analysis revealed how the extract EtOH/H2O 50% (Naviglio and long maceration), along with the extract EtOH/H2O 60% (maceration) were richest in flavonoids. All extracts were tested by TEAC and DPPH assays, and to determine their in vitro antioxidant activity, the DHR 123 probe–intracellular ROS assay in HaCaT cells, for some extracts, was performed. Moreover, their ability to exert a whitening effect was tested by analyzing their tyrosinase inhibitory activity. The quantitative determination of apigenin, known as a natural tyrosinase inhibitor, was performed by LC-ESI/QTrap/MS/MS using the multiple reaction monitoring (MRM) method. These results are promising for selecting an extraction method to obtain a sustainable product rich in bioactives.

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Chemical Profile and Antioxidant and Tyrosinase Inhibitory Activity of Chamaemelum nobile L. Green Extracts

Polcaro,

Cerulli,

Montella

et al. 2024

Cosmetics

View full text Add to dashboard Cite

show abstract

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Special Issue “Anti-Oxidant and Anti-Inflammatory Properties of Natural Compounds”

Abstract: Throughout history, humans have utilized plants as conscious or unconscious sources of molecules for food, health and well-being [...]

Cited by 1 publication

References 13 publications

Chemical Profile and Antioxidant and Tyrosinase Inhibitory Activity of Chamaemelum nobile L. Green Extracts

Chemical Profile and Antioxidant and Tyrosinase Inhibitory Activity of Chamaemelum nobile L. Green Extracts

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