Special Issue: Application of Nanomaterials in Biomedical Imaging and Cancer Therapy

Chow, James C. L.

doi:10.3390/nano12050726

Cited by 18 publications

(5 citation statements)

References 11 publications

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“…A hot trend in current research is to equip rare-earth NPs with therapeutic functions through surface modifications (antibodies, chemotherapeutic agents, or photosensitizers, etc. ), while achieving multimodal imaging of tumor sites [78][79][80][81]. In particular, surface modification with tumor-targeting ligands can enhance the potential of rare-earth NPs for cancer diagnosis and treatment [19].…”

Section: Discussionmentioning

confidence: 99%

Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles

Schomann

et al. 2022

Pharmaceutics

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Nowadays, cancer poses a significant hazard to humans. Limitations in early diagnosis techniques not only result in a waste of healthcare resources but can even lead to delays in diagnosis and treatment, consequently reducing cure rates. Therefore, it is crucial to develop an imaging probe that can provide diagnostic information precisely and rapidly. Here, we used a simple hydrothermal method to design a multimodal imaging probe based on the excellent properties of rare-earth ions. Calcium fluoride co-doped with ytterbium, gadolinium, and neodymium (CaF2:Y,Gd,Nd) nanoparticles (NPs) is highly crystalline, homogeneous in morphology, and displays a high biosafety profile. In addition, in vitro and ex vivo experiments explored the multimodal imaging capability of CaF2:Y,Gd,Nd and demonstrated the efficient performance of CaF2:Y,Gd,Nd during NIR-II fluorescence/photoacoustic/magnetic resonance imaging. Collectively, our novel diagnosis nanoparticle will generate new ideas for the development of multifunctional nanoplatforms for disease diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles

Schomann

et al. 2022

Pharmaceutics

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“…MNPs can be used to target tumors and deliver drugs, imaging agents, and therapeutic agents directly to the site of cancer. There has been significant progress in the development of multifunctional magnetic nanostructures for cancer diagnosis and treatment in recent years [ 191 ]. These nanostructures offer several advantages over traditional methods, including their ability to target specific cancer cells and deliver therapeutic agents with high efficiency.…”

Section: Cancer Therapymentioning

confidence: 99%

A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach

et al. 2023

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The new era of nanomedicine offers significant opportunities for cancer diagnostics and treatment. Magnetic nanoplatforms could be highly effective tools for cancer diagnosis and treatment in the future. Due to their tunable morphologies and superior properties, multifunctional magnetic nanomaterials and their hybrid nanostructures can be designed as specific carriers of drugs, imaging agents, and magnetic theranostics. Multifunctional magnetic nanostructures are promising theranostic agents due to their ability to diagnose and combine therapies. This review provides a comprehensive overview of the development of advanced multifunctional magnetic nanostructures combining magnetic and optical properties, providing photoresponsive magnetic platforms for promising medical applications. Moreover, this review discusses various innovative developments using multifunctional magnetic nanostructures, including drug delivery, cancer treatment, tumor-specific ligands that deliver chemotherapeutics or hormonal agents, magnetic resonance imaging, and tissue engineering. Additionally, artificial intelligence (AI) can be used to optimize material properties in cancer diagnosis and treatment, based on predicted interactions with drugs, cell membranes, vasculature, biological fluid, and the immune system to enhance the effectiveness of therapeutic agents. Furthermore, this review provides an overview of AI approaches used to assess the practical utility of multifunctional magnetic nanostructures for cancer diagnosis and treatment. Finally, the review presents the current knowledge and perspectives on hybrid magnetic systems as cancer treatment tools with AI models.

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“…To get around drug resistance, they often produce drug synergy. 147,148 J. Moore et al used AI, stochastic models, and diagnostic models to increase and obtain the most effective anticancer therapy because these approaches serve in advancing research concerning nanotechnology. They mentioned how the design, size, and functioning were changed.…”

Section: Theranostics Including Imaging and Therapy By Nanocrystalsmentioning

confidence: 99%

Recent advances of nanocrystals in cancer theranostics

Yenurkar,

Nayak,

Mukherjee

2023

Nanoscale Adv.

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Special Issue: Application of Nanomaterials in Biomedical Imaging and Cancer Therapy

Cited by 18 publications

References 11 publications

Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles

Achieving Effective Multimodal Imaging with Rare-Earth Ion-Doped CaF2 Nanoparticles

A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach

Recent advances of nanocrystals in cancer theranostics

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