Special Issue “Function and Structure of Viral Ribonucleoproteins Complexes”

Bernacchi, Serena

doi:10.3390/v12121355

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Viral Structure and Function1

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2021

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“…The second is icosahedral symmetry, in which protein subunits are assembled into a symmetrical shell that surrounds the center of the nucleic acid. Thus, the generated three-dimensional capsid is constructed from repetitive multi-protein subunit copies [ 15 , 16 ].…”

Section: Viral Structure and Functionmentioning

confidence: 99%

The Viral Capsid As Novel Nanomaterials for Drug Delivery

Aljabali

Hassan²,

Pabari

et al. 2021

Future Sci. OA

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The purpose of this review is to highlight recent scientific developments and provide an overview of virus self-assembly and viral particle dynamics. Viruses are organized supramolecular structures with distinct yet related features and functions. Plant viruses are extensively used in biotechnology, and virus-like particulate matter is generated by genetic modification. Both provide a material-based means for selective distribution and delivery of drug molecules. Through surface engineering of their capsids, virus-derived nanomaterials facilitate various potential applications for selective drug delivery. Viruses have significant implications in chemotherapy, gene transfer, vaccine production, immunotherapy and molecular imaging.

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Section: Viral Structure and Functionmentioning

confidence: 99%