Special Issue on “Multifunctional Hybrid Materials Based on Polymers: Design and Performance”

Hamzehlou, Shaghayegh; Aboudzadeh, M. Ali

doi:10.3390/pr9081448

Cited by 8 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hybrid materials are intriguing for a variety of applications due to their properties, which are a result of the synergetic effect of the organic and inorganic components' combination. Polymer-based biocompatible materials have attracted a lot of interest due to the possibility of using them to protect human health and improve the quality of life [6]. As inorganic components' different substances like silanized silica particles [7], graphene/carbon nanotubes [8], bioactive ceramics, and glasses or glass ceramics [9], metallic materials [10], etc., have been used depending on the biomaterial application.…”

Section: Introductionmentioning

confidence: 99%

Polycarboxy/Sulfo Betaine—Calcium Phosphate Hybrid Materials with a Remineralization Potential

Rabadjieva,

Gergulova,

Ruseva

et al. 2023

Materials

View full text Add to dashboard Cite

Biomacromolecules control mineral formation during the biomineralization process, but the effects of the organic components’ functionality on the type of mineral phase is still unclear. The biomimetic precipitation of calcium phosphates in a physiological medium containing either polycarboxybetaine (PCB) or polysulfobetaine (PSB) was investigated in this study. Amorphous calcium phosphate (ACP) or a mixture of octacalcium phosphate (OCP) and dicalcium phosphate dihydrate (DCPD) in different ratios were identified depending on the sequence of initial solution mixing and on the type of the negative functional group of the polymer used. The more acidic character of the sulfo group in PSB than the carboxy one in PCB determines the dominance of the acidic solid phases, namely, an acidic amorphous phase or DCPD. In the presence of PCB, the formation of ACP with acicular particles arranged in bundles with the same orientation was observed. A preliminary study on the remineralization potential of the hybrid material with the participation of PSB and a mixture of OCP and DCPD did not show an increase in enamel density, contrary to the materials based on PCB and ACP. Moreover, the latter showed the creation of a newly formed crystal layer similar to that of the underlying enamel. This defines PCB/ACP as a promising material for enamel remineralization.

show abstract

Section: Introductionmentioning

confidence: 99%

Polycarboxy/Sulfo Betaine—Calcium Phosphate Hybrid Materials with a Remineralization Potential

Rabadjieva,

Gergulova,

Ruseva

et al. 2023

Materials

View full text Add to dashboard Cite

show abstract

“…These hybrid materials have already demonstrated excellent commitment in addressing and offering solutions to the existing challenges in priority areas such as human health, environment and energy [ 10 , 11 , 12 ]. However, their design, performance, and practical applications are still ambitious [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability

et al. 2021

Self Cite

View full text Add to dashboard Cite

Baricitinib (BTB) is an orally administered Janus kinase inhibitor, therapeutically used for the treatment of rheumatoid arthritis. Recently it has also been approved for the treatment of COVID-19 infection. In this study, four different BTB-loaded lipids (stearin)-polymer (Poly(d,l-lactide-co-glycolide)) hybrid nanoparticles (B-PLN1 to B-PLN4) were prepared by the single-step nanoprecipitation method. Next, they were characterised in terms of physicochemical properties such as particle size, zeta potential (ζP), polydispersity index (PDI), entrapment efficiency (EE) and drug loading (DL). Based on preliminary evaluation, the B-PLN4 was regarded as the optimised formulation with particle size (272 ± 7.6 nm), PDI (0.225), ζP (−36.5 ± 3.1 mV), %EE (71.6 ± 1.5%) and %DL (2.87 ± 0.42%). This formulation (B-PLN4) was further assessed concerning morphology, in vitro release, and in vivo pharmacokinetic studies in rats. The in vitro release profile exhibited a sustained release pattern well-fitted by the Korsmeyer–Peppas kinetic model (R2 = 0.879). The in vivo pharmacokinetic data showed an enhancement (2.92 times more) in bioavailability in comparison to the normal suspension of pure BTB. These data concluded that the formulated lipid-polymer hybrid nanoparticles could be a promising drug delivery option to enhance the bioavailability of BTB. Overall, this study provides a scientific basis for future studies on the entrapment efficiency of lipid-polymer hybrid systems as promising carriers for overcoming pharmacokinetic limitations.

show abstract

“…Poly(L-lactic acid) (PLLA) is one of the most widely used and promising bio-based polymers that have already been industrialized. Adding various active agents, such as chitosan and essential basil oil, has been extensively studied to improve the thermal, mechanical, antioxidant, and barrier properties of the composites [3]. Also, polyethylene glycol (PEG)'s solvatable polymer backbone, neutral surface charge, and chemical stability make it one of the most adaptable molecular stabilizers of inorganic nanoparticles [4].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Poly(ethylene furanoate)/Silver and Titanium Dioxide Nanocomposites with Improved Thermal and Antimicrobial Properties

Stanley,

Xanthopoulou,

Zemljič

et al. 2024

Materials

View full text Add to dashboard Cite

Poly(ethylene furanoate) (PEF)-based nanocomposites were fabricated with silver (Ag) and titanium dioxide (TiO2) nanoparticles by the in-situ polymerization method. The importance of this research work is to extend the usage of PEF-based nanocomposites with improved material properties. The PEF-Ag and PEF-TiO2 nanocomposites showed a significant improvement in color concentration, as determined by the color colorimeter. Scanning electron microscopy (SEM) photographs revealed the appearance of small aggregates on the surface of nanocomposites. According to crystallinity investigations, neat PEF and nanocomposites exhibit crystalline fraction between 0–6%, whereas annealed samples showed a degree of crystallinity value above 25%. Combining the structural and molecular dynamics observations from broadband dielectric spectroscopy (BDS) measurements found strong interactions between polymer chains and nanoparticles. Contact angle results exhibited a decrease in the wetting angle of nanocomposites compared to neat PEF. Finally, antimicrobial studies have been conducted, reporting a significant rise in inhibition of over 15% for both nanocomposite films against gram-positive and gram-negative bacteria. From the overall results, the synthesized PEF-based nanocomposites with enhanced thermal and antimicrobial properties may be optimized and utilized for the secondary packaging (unintended food-contact) materials.

show abstract

Special Issue on “Multifunctional Hybrid Materials Based on Polymers: Design and Performance”

Abstract: Hybrids and composite materials offer a synergic combination of polymer and inorganic features [...]

Cited by 8 publications

References 11 publications

Polycarboxy/Sulfo Betaine—Calcium Phosphate Hybrid Materials with a Remineralization Potential

Polycarboxy/Sulfo Betaine—Calcium Phosphate Hybrid Materials with a Remineralization Potential

Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability

Fabrication of Poly(ethylene furanoate)/Silver and Titanium Dioxide Nanocomposites with Improved Thermal and Antimicrobial Properties

Contact Info

Product

Resources

About