Special Issue: “Organic Reactions in Green Solvents”

Abstract

Abstract:To overcome the well-established drawbacks of conventional organic solvents (toxicity, non-biodegradability, flammability, accumulation in the atmosphere) remarkable research efforts have been recently devoted to the replacement of traditional organic reaction media by the so-called Green Solvents. In this sense, the choice of a safe, non-toxic, biorenewable and cheap reaction media is a crucial goal in organic synthesis. Thus, this Special Issue on "Organic Reactions in Green Solvents" has been aimed to showcase a series of stimulating contributions from international experts within different sub-areas of organic synthesis in Green Solvents (ranging from metal-to organo-catalyzed organic reactions).

Ultrasonication‐Assisted Synthesis of 3‐Substituted Indoles in Water Using Polymer Grafted ZnO Nanoparticles as Eco‐Friendly Catalyst

“…In the last few decades, increasing awareness to develop environmentally friendly protocols has prompted use of water and mixed aqueous solvents in organic transformation. Reactions conducted in water are cheaper, safe, reduce environmental pollution and in many cases enhances selectivity ,. It has been noted that most of the organic reactions proceed sluggishly in water because of poor solubility of reactants, though, according to Breslow effect hydrophobic aggregation of organic molecules reduces the activation energy .…”

Synthesis and antidiabetic activity of novel triazole derivatives containing amino acids

“…The development of green, benign, environment friendly and economical methods is needed to reduce the harmful effects of volatile solvents and catalysts that are currently used in drug synthesis. The use of water as a unique green solvent has attracted a lot of attention . Similarly, natural catalysts such as citrus limonium, extract species of lemon juice represent a unique category of biocatalysts that have a vast number of applications in the organic synthesis .…”

Nanoreactors for green catalysis

“…Generally, using water as a solvent is an acceptable choice for green chemistry [ 4 – 6 ]. Indeed, water is attractive from both economic and environmental points of view, and is not taken into account when the E-factor (defined as mass ratio of waste to desired product) for a chemical process is determined [ 7 – 8 ]. This is to be true for chemical processes where the utility of water is limited to the work-up at the end of the process and not when used as a reaction medium.…”