Special Issue: “Telomerase: Role in Health and Aging”

Yegorov, Yegor E.

doi:10.3390/biomedicines10112957

Biomedicines

2022

DOI: 10.3390/biomedicines10112957

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Special Issue: “Telomerase: Role in Health and Aging”

Yegor E. Yegorov

Abstract: We would like to introduce the new volume: “Telomerase and Telomeres: Its Role in Health and Aging 2 [...]

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Olovnikov, Telomeres, and Telomerase. Is It Possible to Prolong a Healthy Life?

Yegorov

2023

Biochemistry Moscow

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The science of telomeres and telomerase has made tremendous progress in recent decades. In this review, we consider it first in a historical context (the Carrel–Hayflick–Olovnikov–Blackburn chain of discoveries) and then review current knowledge on the telomere structure and dynamics in norm and pathology. Central to the review are consequences of the telomere shortening, including telomere position effects, DNA damage signaling, and increased genetic instability. Cell senescence and role of telomere length in its development are discussed separately. Therapeutic aspects and risks of telomere lengthening methods including use of telomerase and other approaches are also discussed.

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Olovnikov, Telomeres, and Telomerase. Is It Possible to Prolong a Healthy Life?

Yegorov

2023

Biochemistry Moscow

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Olovnikov, telomeres and telomerase. is it possible to prolong a healthy life?

Yegorov

2023

Biohimiâ

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The science of telomeres and telomerase has made tremendous progress in recent decades. In this review, we consider it first in a historical context (the Carrel-Hayflick-Olovnikov-Blackburn chain of discoveries) and then review current knowledge of telomere structure and dynamics in norm and pathology. Central to the review are the consequences of telomere shortening, including telomere position effects, DNA damage signaling, and increased genetic instability. Cell senescence and the role of telomere length in its development are discussed separately. Therapeutic aspects and risks of telomerase and other telomere lengthening methods are also discussed.

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Special Issue: “Telomerase: Role in Health and Aging”

Abstract: We would like to introduce the new volume: “Telomerase and Telomeres: Its Role in Health and Aging 2 [...]

Cited by 2 publications

References 16 publications

Olovnikov, Telomeres, and Telomerase. Is It Possible to Prolong a Healthy Life?

Olovnikov, Telomeres, and Telomerase. Is It Possible to Prolong a Healthy Life?

Olovnikov, telomeres and telomerase. is it possible to prolong a healthy life?

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