Obesity, defined as a body mass index of >30 kg/m 2 , 1 occurs when excess fat accumulation (regionally and/or globally) increases adverse health risks. With a global surge in prevalence, obesity and its associated comorbidities exert a significant economic and health burden on our society. Obesity is known to increase the risk of several chronic conditions, including type 2 diabetes, cancer, and cardiovascular diseases. 2 Additionally, new evidence is emerging to show a potential bidirectional relationship between obesity and periodontal disease. 3,4 The recent 2017 classification of periodontal diseases and conditions recognized obesity as a systemic factor affecting periodontal health. In particular, the role of obesity in worsening periodontal inflammation and in increasing the risk of developing periodontitis has been recognized. 5 Exploring the potential link between obesity and periodontal disease is currently an area of active research, and the shared molecular and environmental underpinnings between obesity and periodontal disease have been comprehensively reviewed by several groups. 3,[6][7][8][9][10] However, literature on the logistics of managing this special cohort remain scarce.With more than one-third of US adults being overweight or obese, encountering these patients in periodontal practices is a routine occurrence. Therefore, in addition to reviewing the biologic interlinks between obesity and periodontal disease, this review delineates practical considerations for managing these patients in an everyday periodontal practice setting.