Last year, we celebrated the 125th anniversary of medical imaging based on Röntgen's discovery. 1 One of the first radiographs was his wife's hand with a metallic ring that has been replicated numerous times. These early radiographs showed impressive details of bone structures. Thanks to tomographic imaging, introduced five decades ago 2 and extended to the micrometer scale four decades ago, 3 trabecular bone can now be visualized three-dimensionally with isotropic, submicrometer resolution. This special section of the Journal of Medical Imaging (JMI) marks this anniversary with a collection of eight contributions, mainly based on the SPIE Conference "Developments in X-ray Tomography XIII" which occurred in San Diego, California, August 2-3, 2021, with both physical and remote participation. 4 Despite the inconvenience caused by traveling restrictions, the traditional exchange of ideas and brainstorming was continued via on-site discussion, on-line presentation, and off-line Slack communication. The submission of more than 50 contributions demonstrated the momentum of the advancement in research, development, and applications. The success of this conference series inspired us to organize this special section as a snapshot, albeit limited, of this important niche area featured by hard x-ray tomography at the micrometer level.The article by S. Alloo et al. is on dark-field tomography through intrinsic x-ray speckletracking (