Special type breast carcinoma: Sebaceous carcinoma of the breast; A case report and review of literature

Abstract

Sebaceous carcinoma of the breast is an extremely rare tumor. To the best of our knowledge only 15 cases have been reported in literature. Herein, we report a case of sebaceous carcinoma of the breast and describe the histopathologic features of sebaceous carcinoma of the breast in an elderly female.

Invasive Breast Carcinoma With Sebaceous Morphologic Pattern Showing Lymph Node Macrometastasis: A Case Report

“…SC is a rare malignant tumor that originates from the sebaceous glands and can occur in any body site where sebaceous glands are present [ 4 ]. SC is most commonly found in the periocular area.…”

“…SC is most commonly found in the periocular area. Although extraocular SC is infrequent, it can occur in the major salivary glands, oral mucosa, breasts, lungs, and ovaries [ 4 ]. Primary breast SC is an extremely rare type of breast tumor and is classified as a sebaceous pattern of IDC-NST in the fifth edition of the WHO breast tumor classification system.…”

“…Due to the limited clinical evidence, the current fifth edition of the WHO classifies it as a special morphologic subtype of invasive breast carcinoma of no special type regardless of the extent of the pattern. Because of its rare occurrence, its behavior and prognosis are not well understood yet [ 4 ]. In this report, we present a case of breast carcinoma with sebaceous differentiation that caused metastasis to the axillary lymph node.…”