Specific dermoscopic findings in glomeruloid haemangioma for diagnosis of POEMS syndrome

Abstract

Dear Editor, A 56-year-old man was referred to the Dermatology Department for evaluation of several haemangiomas on his trunk. The patient was admitted to the hospital and closely examined for numbness and muscle weakness in his extremities, which started a year ago. During the physical examination, multiple haemangiomas were found on his trunk with a maximum size of 6 mm and a bright red appearance (Figure 1a). Although no difference from cherry haemangioma could be found on physical examination, dermoscopic examination revealed vascular findings consisting of a combination of red lacunae (Figure 1b, arrowheads) and liner irregular vessels without branching (Figure 1b, arrows). This specific dermoscopic finding was also seen

Red Nodule on the Scalp in a Healthy Young Man

“…2,8 On dermoscopic examination, GH displays red lacunae and/or red-white backgrounds, linear irregular vessels, and red rounded structures. 6,7 In the present case, PH dermoscopic findings showed red lacunae without septa, white structureless areas, and irregular vessels. These findings have not been previously described.…”

“…Clinically, GH presents as multiple, small, red papules on the trunk and limbs, with a rapid onset of days or few weeks. 6,7 In contrast, PH presents in adults as a solitary tumor on the head and neck. Additionally, GH is considered to be a hallmark finding of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, skin changes) 6 and TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly) syndromes.…”