Specific Detection of Short-Chain Alcohols, with the Development of an Enzyme-Coated Microcantilever-Based Biosensor

Margarido, Alexandre; Manzine, Lívia Regina; Araujo-Moreira, Fernando M.; Gonçalves, Renato V.; Herrmann, P. S. de P.

doi:10.1007/s13538-022-01111-w

Cited by 2 publications

(3 citation statements)

References 26 publications

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“…Biosensor used for sending volatile ethanol, propanol and butanol [179] Yeast alcohol dehydrogenase (yADH) Polyaniline-coated silver nanoparticles At 70 °C, immobilized YADH retained about 78 % activity as compared to 26 % retained by the soluble enzyme.…”

Section: Agarose Matrixes Using Glyoxyl Chemistrymentioning

confidence: 99%

Stairway to Stereoisomers: Engineering Short‐ and Medium‐Chain Ketoreductases To Produce Chiral Alcohols

Shanbhag

2023

ChemBioChem

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The short-and medium-chain dehydrogenase/reductase superfamilies are responsible for most chiral alcohol production in laboratories and industries. In nature, they participate in diverse roles such as detoxification, housekeeping, secondary metabolite production, and catalysis of several chemicals with commercial and environmental significance. As a result, they are used in industries to create biopolymers, active pharmaceutical intermediates (APIs), and are also used as components of modular enzymes like polyketide synthases for fabricating bioactive molecules. Consequently, random, semi-rational and rational engineering have helped transform these enzymes into product-oriented efficient catalysts. The rise of newer synthetic chemicals and their enantiopure counterparts has proved challenging, and engineering them has been the subject of numerous studies. However, they are frequently limited to the synthesis of a single chiral alcohol. The study attempts to defragment and describe hotspots of engineering short-and medium-chain dehydrogenases/reductases for the production of chiral synthons.

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Section: Agarose Matrixes Using Glyoxyl Chemistrymentioning

confidence: 99%

Stairway to Stereoisomers: Engineering Short‐ and Medium‐Chain Ketoreductases To Produce Chiral Alcohols

Shanbhag

2023

ChemBioChem

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“…Alcohols are also considered prime composition in household belongings, e. g., hand sanitizers, printing works, paints, colors, toiletries, etc. Prolonged exposure to alcohol vapors harms human health and may cause eye irritation, dizziness, damage to the nervous system, and sometimes even be fatal [1] . Alcohol vapors can be detected using various sensors, which may operate based on the change of optical absorption, electrical conductivity, electrochemical signal, etc [2] .…”

Section: Introductionmentioning

confidence: 99%

“…Prolonged exposure to alcohol vapors harms human health and may cause eye irritation, dizziness, damage to the nervous system, and sometimes even be fatal. [1] Alcohol vapors can be detected using various sensors, which may operate based on the change of optical absorption, electrical conductivity, electrochemical signal, etc. [2] Amongst these sensors, semiconducting metal oxide (SMO)-based chemiresistive gas/ vapor sensors are popular because of their simple operation, low cost, alongwith promising reproducible sensing characteristics with reasonable durability.…”

Section: Introductionmentioning

confidence: 99%

Autocombustion Route Derived Zinc Ferrite Nanoparticles as Chemiresistive Sensor for Detection of Alcohol Vapors

Bhagat,

Gupta,

Mandal

et al. 2024

ChemPhysChem

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Prolonged exposure to alcohol vapors can have detrimental effects on human health, potentially leading to eye irritation, dizziness, and in some cases, damage to the nervous system. The present article aims to provide a comprehensive understanding on the synthesis and characterization of zinc ferrite (ZnFe2O4) nanoparticles, as well as their interactions with a range of alcohol vapors, including methanol, ethanol, n‐propanol, and isopropanol. These alcohols differ in their molecular weight, boiling points, diffusivity, and other properties. The study reveals the semiconducting ZnFe2O4 nanoparticulate sensor's capability for reversible, repeatable, and sensitive detection of alcohol vapors. The sensor exhibits the highest response to ethanol within operating temperature range (225‐300°C). An attempt is made to establish a correlation between the properties of the target analytes and the observed sensing signals. Additionally, the response conductance transients of ZnFe2O4 under the exposure to the studied alcohol vapors are modeled based on the Langmuir‐Hinshelwood adsorption mechanism. The characteristic time constants obtained from this modeling are justified with respect to the properties of the analytes.

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Specific Detection of Short-Chain Alcohols, with the Development of an Enzyme-Coated Microcantilever-Based Biosensor

Cited by 2 publications

References 26 publications

Stairway to Stereoisomers: Engineering Short‐ and Medium‐Chain Ketoreductases To Produce Chiral Alcohols

Stairway to Stereoisomers: Engineering Short‐ and Medium‐Chain Ketoreductases To Produce Chiral Alcohols

Autocombustion Route Derived Zinc Ferrite Nanoparticles as Chemiresistive Sensor for Detection of Alcohol Vapors

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