Specific targeting of ultrasound contrast agent (USCA) for diagnostic application: an in vitro feasibility study based on SAW biosensor

Joseph, Shiba; Gronewold, Thomas M. A.; Schlensog, Marc Dominic; Olbrich, Carsten; Quandt, Eckhard; Famulok, Michael; Schirner, Michael

doi:10.1016/j.bios.2004.07.014

Cited by 21 publications

(10 citation statements)

References 15 publications

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“…Detection is performed by measuring changes in signal amplitude and phase. Experimental results obtained with this commercial biosensor have been reported by some groups [108,114–118]. Other commercially available system is the SAW-MDK1 (Senseor, Mougins, France), which consists of a microbalance development kit with two-channel delay lines based on LW devices, but no results derived from their applications have been reported yet.…”

Section: Commercial Sgaw-based Biosensors Trends and Challengesmentioning

confidence: 99%

Surface Generated Acoustic Wave Biosensors for the Detection of Pathogens: A Review

Rocha-Gaso

March-Iborra

Montoya-Baides

et al. 2009

Sensors

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This review presents a deep insight into the Surface Generated Acoustic Wave (SGAW) technology for biosensing applications, based on more than 40 years of technological and scientific developments. In the last 20 years, SGAWs have been attracting the attention of the biochemical scientific community, due to the fact that some of these devices -Shear Horizontal Surface Acoustic Wave (SH-SAW), Surface Transverse Wave (STW), Love Wave (LW), Flexural Plate Wave (FPW), Shear Horizontal Acoustic Plate Mode (SH-APM) and Layered Guided Acoustic Plate Mode (LG-APM) -have demonstrated a high sensitivity in the detection of biorelevant molecules in liquid media. In addition, complementary efforts to improve the sensing films have been done during these years. All these developments have been made with the aim of achieving, in a future, a highly sensitive, low cost, small size, multi-channel, portable, reliable and commercially established SGAW biosensor. A setup with these features could significantly contribute to future developments in the health, food and environmental industries. The second purpose of this work is to describe the state-of-the-art of SGAW biosensors for the detection of pathogens, being this topic an issue of extremely importance for the human health. Finally, the review discuses the commercial availability, trends and future challenges of the SGAW biosensors for such applications.

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Section: Commercial Sgaw-based Biosensors Trends and Challengesmentioning

confidence: 99%

Surface Generated Acoustic Wave Biosensors for the Detection of Pathogens: A Review

Rocha-Gaso

March-Iborra

Montoya-Baides

et al. 2009

Sensors

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“…Calorimetric devices such as thermister have been also used for the measurement of the thermal change by the reaction heat (exothermal and endothermal) at those enzymatic reactions (Rajkumar et al, 2008;Ramanathan and Danielsson, 2001;Urban et al, 1991). In addition, mass changes caused by intermolecular reactions can be assessed by Quartz Crystal Microbalance (QCM) or Surface Acoustic Wave (SAW) devices (Briand et al, 2007;Fatoyinbo et al, 2007;Ogi et al, 2007;Gronewold et al, 2005;Joseph et al, 2005;Martin et al, 2004). However, a chemo-mechanical conversion device for biosensor and biological measurements has not been reported.…”

Section: Introductionmentioning

confidence: 98%

Tonometric biosensor with a differential pressure sensor for chemo-mechanical measurement of glucose

Mitsubayashi

Ohgoshi

Okamoto

et al. 2009

Biosensors and Bioelectronics

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“…SAW based RFID) reported to date operate on a unifying principle which is to modulate the lumped electrical impedance seen at the terminals of an RFID antenna. Some of the examples include surface acoustic wave (SAW) based RFID biosensors [1], [2] or molecular imprinted polymer (MIP) films based RF biosensor [3] and split-ring resonator (SRR) based RF biosensor [4].…”

Section: Introductionmentioning

confidence: 99%

A Novel Biosensor Based on Silver-Enhanced Self-Assembled Radio-Frequency Antennas

2014

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In this letter, we show that a silver-enhancement technique can be used to self-assemble a radio-frequency (RF) antenna, which then can be used for designing a radio-frequency identification (RFID)-based biosensor. Using the proposed biosensor, the concentration of target analytes or pathogens can be remotely interrogated in a concealed, packaged, or in a biohazardous environment, where direct measurement is considered to be impractical. In the presence of the target analytes or pathogens, a silver-enhancement process self-assembles a chain of micromonopole antennas. As the size of the silver-enhanced particles grow, the chain of microantenna segments bridges together to complete a dipole structure that reflects impinging RF signals at a desired frequency. We validate the proof-of-concept for IgG detection and demonstrate that different concentrations of rabbit IgG (ranging from 20 to 60 ng in this letter) can be detected based on the strength of the reflected RF signal received at a 915-MHz COTS RFID reader.Index Terms-Micro-antennas, wireless detection, RFID, silver enhancement, biosensor.

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Specific targeting of ultrasound contrast agent (USCA) for diagnostic application: an in vitro feasibility study based on SAW biosensor

Cited by 21 publications

References 15 publications

Surface Generated Acoustic Wave Biosensors for the Detection of Pathogens: A Review

Surface Generated Acoustic Wave Biosensors for the Detection of Pathogens: A Review

Tonometric biosensor with a differential pressure sensor for chemo-mechanical measurement of glucose

A Novel Biosensor Based on Silver-Enhanced Self-Assembled Radio-Frequency Antennas

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