2024
DOI: 10.1038/s41467-024-45695-0
|View full text |Cite|
|
Sign up to set email alerts
|

Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Kyung Ah Han,
Taek-Han Yoon,
Jinhu Kim
et al.

Abstract: LAR-RPTPs are evolutionarily conserved presynaptic cell-adhesion molecules that orchestrate multifarious synaptic adhesion pathways. Extensive alternative splicing of LAR-RPTP mRNAs may produce innumerable LAR-RPTP isoforms that act as regulatory “codes” for determining the identity and strength of specific synapse signaling. However, no direct evidence for this hypothesis exists. Here, using targeted RNA sequencing, we detected LAR-RPTP mRNAs in diverse cell types across adult male mouse brain areas. We found… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
references
References 93 publications
0
0
0
Order By: Relevance