The theory of speckle dynamics in the image plane of a reflecting and thin transparent object is considered. It was assumed that the optical paths of the reflected and probing transparent object waves vary due to (1) translational motion, (2) oscillations with a period T, and (3) random relative displacements of pairs of scattering centers Δu (reflecting object) and random changes in the refractive index Δn (transparent object). The formulas relating the mean value, dispersion, and relaxation time of Δu and Δn values with the time-averaged radiation intensity at the observation point and the time autocorrelation function of this intensity are obtained. It is shown that at the averaging time multiple of T, the technique in real time allows to determine plastic deformations of the order of 10 À3 on bases of the order of 10 microns, which is suitable for the control of elastic deformations on bases of the order of 100 microns. The possibilities of the method of averaged speckle images for the study of (1) features of the nucleation, start, and movement of the fatigue crack, and (2) the activity of living cells infected and not infected with the virus are demonstrated.