We present relative astrometric measurements of visual binaries, made in 2009 with the speckle camera PISCO at the 102 cm Zeiss telescope of Brera Astronomical Observatory, in Merate. Our observing list contains orbital couples as well as binaries whose motion is still uncertain. We obtained 345 new measurements of 259 objects, with angular separations in the range 0. 18-4. 6, and an average accuracy of 0. 011. The mean error on the position angles is 0.• 6. Most of the position angles were determined without the usual 180• ambiguity with the application of triple-correlation techniques and/or by inspection of the long integration files. We have found a possible new close component for ADS 2377, which would be a new quadruple star system. We also present new revised orbits for ADS 8035, 9982, 11484, and MLR 198, partly derived from those observations, and infer estimated values for the masses of those systems that are compatible with the spectral types.