2011
DOI: 10.1117/1.3652713
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Speckle reduction in optical coherence tomography imaging by affine-motion image registration

Abstract: Abstract. Signal-degrading speckle is one factor that can reduce the quality of optical coherence tomography images. We demonstrate the use of a hierarchical model-based motion estimation processing scheme based on an affine-motion model to reduce speckle in optical coherence tomography imaging, by image registration and the averaging of multiple B-scans. The proposed technique is evaluated against other methods available in the literature. The results from a set of retinal images show the benefit of the propo… Show more

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Cited by 71 publications
(51 citation statements)
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“…The details of this processing method have been presented elsewhere. 23 The final outcome of each animation mode measurement is a single averaged B-scan with reduced noise and subsequently with a clearer distinction between tissue layers. Fig.…”
Section: Methods For Oct Data Acquisition and Analysismentioning
confidence: 99%
“…The details of this processing method have been presented elsewhere. 23 The final outcome of each animation mode measurement is a single averaged B-scan with reduced noise and subsequently with a clearer distinction between tissue layers. Fig.…”
Section: Methods For Oct Data Acquisition and Analysismentioning
confidence: 99%
“…36 These averaged images then were analyzed by two independent masked observers to manually segment the outer border of the RPE and the inner border of the chorioscleral interface across the 6 mm length of each scan to determine choroidal thickness. Each observer manually selected a series of points along the two boundaries, and a smooth function (a series of spline fits) then was fit automatically to these points to define the boundaries (initially the observers used 14 points along each boundary, but additional points could be added by the observers if the resulting line did not fit the boundary adequately).…”
Section: Discussionmentioning
confidence: 99%
“…Incoherent averaging of these decorrelated images reduces the speckle noise [18,19]. In another method, image registration followed by averaging of multiple B-scans is used to reduce speckle [20].…”
Section: Speckle Reduction and Signal Improvementmentioning
confidence: 99%