SPECT-CT visualization and biopsy of sentinel lymph nodes in patients with stage IAB–IIA cervical cancer

Новиков, С. Н.; Крживицкий, П. И.; Kanaev, Sergey; Berlev, I; Bisyarin, M.; Artemyeva, Anna

doi:10.1007/s12149-020-01503-5

Cited by 4 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hoogendam et al 10 reported that the overall detection rate of SLN by SPECT/CT was 93.1%, whereas the overall detection rate with LSG was 91% in patients with cervical cancer. Previous studies have shown that the overall identification rates of SLNs by SPECT/CT or LSG are 92.2% to 100% 6,8–12 and 70% to 100%, 6,8–10 respectively (Table 4). Many studies have reported that SPECT/CT for preoperative localization can improve the SLN identification rate compared with LSG for various types of cancer 13,14 .…”

Section: Discussionmentioning

confidence: 95%

Validation of single‐photon emission computed tomography with computed tomography and lymphoscintigraphy for sentinel lymph node identification in cervical cancer

Togami

Tokudome

Fukuda

et al. 2023

Intl J Gynecology & Obste

View full text Add to dashboard Cite

ObjectiveTo compare single‐photon emission computed tomography with computed tomography (SPECT/CT) and lymphoscintigraphy (LSG) for the detection of sentinel lymph nodes (SLNs) in patients with early‐stage cervical cancer.MethodsThis hospital‐based, single‐center, retrospective study included 128 patients with cervical cancer (aged >18 years) treated between 2014 and 2022. Injection of 99 m Technetium‐labeled phytate into the uterine cervix was used to detect pelvic SLNs. SNL identification rates and locations were analyzed for preoperative LSG and SPECT/CT.ResultsMedian age and body mass index of patients were 40 years (range, 20–78 years) and 21.7 kg/m2 (range, 16–40 kg/m2), respectively. There was no significant difference in overall identification rates (identification of at least one SLN) of SLNs between SPECT/CT (91%) and LSG (88%). There was no significant difference in bilateral SLN identification rates between SPECT/CT (66%) and LSG (65%). A total of 219 pelvic SLNs (110 right and 109 left hemipelvis) were identified by SPECT/CT; the most frequent locations were the obturator (122 SLNs, 56%) and external iliac (67 SLNs, 30%).ConclusionSPECT/CT and LSG showed high SLN identification rates in patients with cervical cancer, and there was no significant difference in overall or bilateral SLN identification rates between the two techniques.

show abstract

Section: Discussionmentioning

confidence: 95%

Validation of single‐photon emission computed tomography with computed tomography and lymphoscintigraphy for sentinel lymph node identification in cervical cancer

Togami

Tokudome

Fukuda

et al. 2023

Intl J Gynecology & Obste

View full text Add to dashboard Cite

show abstract

“…В настоящее время имеются сообщения об использовании данных радионуклидной визуализации путей лимфооттока от первичной опухоли при определении топографии радиационных полей у больных раком молочной железы, предстательной железы, раком шейки матки [1,3,13,21]. рядом авторов [8,10,20] было высказано предположение, что указанные подходы могут быть использованы при планировании лучевой терапии у больных злокачественными новообразованиями головы и шеи.…”

unclassified

Spect-Ct Visualization of Sentinel Lymph Nodes and Lymph Flow From Tongue Cancer

Kanaev¹,

Novikov²,

Krzhivitskiy³

et al. 2019

Problems in oncology

View full text Add to dashboard Cite

The main purpose of the study was to determine distribution of sentinel lymph nodes in patients with tongue cancer. SPECT-CT visualization of sentinel lymph nodes was performed in 19 primary patients with clinically T1-2N0M0 tongue cancer. SPECT-CT acquisition started 60-120 min after peritumoral injections of 99mTc-nannocolloids (100-150MBq in 0.3-0.4ml). Finally we analyzed lymph flow patterns and localization of lymph nodes with radiocolloids uptake. Bilateral lymph flow from the tongue cancer was detected in 9 (47%) of 19 patients. In 6 cases bilateral pattern was associated with tumors less than 5mm from medial sulcus of the tongue. On the contrary, in 9 of 10 patients with lesions more than 4mm from medial sulcus we detected monolateral lymph-flow. In 4 (21%) of 19 patients SPECT-CT visualized sentinel lymph nodes only in groups Ib-IIa. Modeling of radiotherapy with with standard and lymph-flow guided radiation fields was performed on Eclips treatment planning station. It demonstrated that with lymph-flow guided strategy irradiated volumes can be reduced from 1224 cm3 to 367 cm3, dose to spinal cord can be reduced from 24,7Gy to 14.3Gy, medial dose to contralateral parotid gland - from 24,6Gy to 12,4 Gy. SPECT-CT with radiocolloids can be successfully used for visualization of lymph flow from the primary tumour and subsequent radiotherapy planning.

show abstract

SPECT/CT in Sentinel Node Scintigraphy

Olmos

Vidal-Sicart

2021

Clinical Applications of SPECT-CT

View full text Add to dashboard Cite

SPECT-CT visualization and biopsy of sentinel lymph nodes in patients with stage IAB–IIA cervical cancer

Cited by 4 publications

References 20 publications

Validation of single‐photon emission computed tomography with computed tomography and lymphoscintigraphy for sentinel lymph node identification in cervical cancer

Validation of single‐photon emission computed tomography with computed tomography and lymphoscintigraphy for sentinel lymph node identification in cervical cancer

Spect-Ct Visualization of Sentinel Lymph Nodes and Lymph Flow From Tongue Cancer

SPECT/CT in Sentinel Node Scintigraphy

Contact Info

Product

Resources

About