SPECT des Gehirnes mit^99mTc-HMPAO bei Patienten mit zerebrovaskulärer Erkrankung: Vergleich mit der CT

Abstract

In a retrospective study the sensitivity of SPECT and CT in detecting changes in cerebrovascular disease is compared, based on a group of one hundred patients. The higher sensitivity of SPECT with regard to right-positive results, especially in TIA and PRIND and the markedly lower number of false-negative results are underlined and discussed. The fact that both methods reveal only a slight sensitivity regarding the detection of changes in the basal regions of the brain is also pointed out, with SPECT proving to be the more sensitive of the two methods.

Clinical Usefulness of Technetium-99m HMPAO SPECT Imaging to Map the Ischemic Lesion in Acute Stroke: A Reevaluation

“…Similar results have been reported by Feld man et al [24] and De Roo et al [26] but not by others who noted a higher SPECT sensitivity mostly in small series [15,16,[19][20][21][22] but one [25], Some authors [23,24] have reported a higher sensitivity when SPECT was per formed early after the onset. Similarly, our data show, but not significantly, a higher sensitivity within 24 h. The sen sitivity decreased on day 2, probably because of a sponta neous reperfusion mechanism and increased after day 3.…”

“…Although N-isopropyl-(l2-'I)-p-iodoamphetamine or HMPAO SPECT sensitivity has already been studied by many authors [14][15][16][17][18][19][20][21][22][23][24], we found very few large series [25,26] and none o f them with a purely clinical approach in routine use. Results of previously published reports are summarized in table 5.…”