Asymmetric Hydrogenation of N-Alkyl Ketimines with Phosphine-Free, Chiral, Cationic Ru-MsDPEN Catalysts. -A wide range of N-alkyl imines is efficiently hydrogenated under mild conditions using a chiral Ru catalyst in the presence of Boc2O to give the corresponding N-Boc-protected amines in excellent enantioselectivity (up to 98% e.e.). The reaction can be carried out under environmentally friendly solvent--free conditions, although with slightly lower enantioselectivities. The synthesis of enantiopure N-Boc-protected sertraline (XI) is smoothly achieved using this method. - (CHEN, F.; WANG, T.; HE, Y.; DING, Z.; LI, Z.; XU, L.; FAN*, Q.-H.; Chem. Eur.