Spectral Domain-Optical Coherence Tomography Study of Retinas With a Normal Foveal Contour and Thickness After Retinal Detachment Surgery

Abstract

Disruption of the IS and OS junction could be a surrogate measure of the structural and functional health of the photoreceptors and can explain poor visual outcome in postsuccessful retinal detachment surgery with an otherwise normal foveal contour and thickness.

Association of Spectral-Domain Optical Coherence Tomography Findings with Visual Outcome of Macula-Off Rhegmatogenous Retinal Detachment Surgery

“…In addition, we demonstrated that the integrity of backreflection on baseline SD OCT was significantly correlated with postoperative integrities of ELM and the photoreceptor layer in these patients. Previous studies have found that postoperative integrities of the ELM and photoreceptor IS/OS junction were disrupted in RRD patients with poor visual outcomes after successful surgery [23,24,25,26,27]. From these findings, the status of smudged photoreceptor layers described as ‘backreflection' on preoperative SD OCT may be a useful predictive factor for the postoperative visual outcome in macula-off RRD patients, although the precise status of the photoreceptor IS/OS junction and ELM integrities were difficult to analyze.…”

“…Undulation of the separated outer retina was found to be associated with visual outcome [18,19], and the height of the subretinal fluid beneath the fovea on OCT scans has been suggested as a prognostic factor because it can disturb the interaction between the neurosensory retina and the retinal pigment epithelium [19]. In addition, the postoperative status of the photoreceptor inner segment (IS)/outer segment (OS) junction or the ellipsoid zone and external limiting membrane (ELM) have been used to predict the visual outcome in RRD patients [22,23,24,25,26,27]. …”

Early Simultaneous Fundus Autofluorescence and Optical Coherence Tomography Features After Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment

“…[4][5][6][7] Spectral-domain OCT has allowed detailed study of such abnormalities and in addition has provided important insights about morphologic and structural changes occurring at the level of the external limiting membrane and photoreceptor inner segment/outer segment (IS/OS) junction, which may relate to the integrity of the photoreceptor layer. [8][9][10][11] Fundus autofluorescence (FAF) imaging is a modality that relies on the fluorescence generated from the bisretinoids of lipofuscin in retinal pigment epithelial (RPE) cells and is influenced by absorbing or autofluorescent material anterior to the RPE monolayer. [12][13][14] Given these characteristics, it represents an excellent and noninvasive tool to study the outer retinal layers.…”

Persistent subfoveolar fluid following retinal detachment surgery: an SD-OCT guided study on the incidence, aetiological associations, and natural history

“…OCT studies following successful surgery have reported the recovery of outer retinal layers with the presence of an intact or improved EZ layer correlating with visual acuity. 6,[19][20][21][22] The integrity of the ELM layer has also been reported to be important for visual recovery. [20][21][22] The retrospective observational design and limited size of this study gives rise to potential confounders regarding the interpretation of the acuity outcome, most notably, duration of foveal involvement prior to surgical repair, the development if any of secondary cataract and nonsystematic final follow-up.…”