Spectrophotometric Determination of Escitalopram in Pharmaceuticals

Abstract

ABSTRACT:A new, simple, fast and sensitive two spectrophotometric methods has been developed for determination of Escitalopram in bulk and tablet dosage forms. The method A is based on the oxidation of Escitalopram by a known excess of bromate-bromide mixture in hydrochloric acid medium, reduction of the residual oxidant by a fixed amount of iron(II) and the formation of iron(III)-thiocyanate-complex which is measured at 480 nm. In the method B, 1,10-phenanthroline is used as a complexing agent and the formation of iron(II)-1,10-phenanthroline, which is measured at 510 nm. The methods obeys Beer's law in the concentration range of 0.5 -8.0 µg mL -1 and 0.5-6.5 µg mL , respectively. The methods have been successfully applied to the determination of Escitalopram in pure and dosage forms.

Comparison of Kinetics of Adsorption of Permanganate on Co-Al-Layered Double Hydroxide and MoS2 Nanocompounds

“…In some adsorption processes, depending on the nature of adsorbent or adsorbate, it is possible to observe more than one curve. A number of examples chosen from published papers 50,[54][55][56][57][58][59][60][61][62][63][64] were analyzed by the KASRA model, Table 1 and Fig. S3 and the NIPPON equation, Table 2 and Fig.…”