Spectrophotometric determination of monosodium glutamate in instant noodles’ seasonings and Chinese salt by ligand exchange complexation

Elattar, Rehab H; Kamal, Amira H.; Mansour, Fotouh R.; El‐Malla, Samah F.

doi:10.1016/j.jfca.2023.105404

Cited by 6 publications

(1 citation statement)

References 37 publications

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“…The effects of MSG administration on the brain included elevated cation levels, oxidative stress, inflammation, and AChE and LDH activities and decreased GABA levels in order to induce cognitive impairments in rats via excitotoxic pathways ( Kumar et al, 2021 ). Recently, monosodium glutamate was validated using a straightforward green spectrophotometric approach, and a good correlation between the seasoning for instant noodles and Chinese salt was seen ( Elattar et al, 2023 ). Recent pieces of evidence also suggest the potential of monosodium glutamate-exposed rats to promote oxidative, apoptotic, and inflammatory challenges, which supposes the need to understand the potential risk of MSG intake among humans ( Albrakati, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer’s disease-like animal model

Ankul,

Chandran,

Anuragh

et al. 2023

Front. Pharmacol.

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This systematic review analyzes monosodium glutamate (MSG) in the Alzheimer’s disease-like condition to enhance translational research. Our review seeks to understand how MSG affects the brain and causes degenerative disorders. Due to significant preclinical data linking glutamate toxicity to Alzheimer’s disease and the lack of a comprehensive review or meta-analysis, we initiated a study on MSG’s potential link. We searched PubMed, ScienceDirect, ProQuest, DOAJ, and Scopus for animal research and English language papers without time constraints. This study used the PRISMA-P framework and PICO technique to collect population, intervention or exposure, comparison, and result data. It was registered in PROSPERO as CRD42022371502. MSG affected mice’s exploratory behaviors and short-term working memory. The brain, hippocampus, and cerebellar tissue demonstrated neuronal injury-related histological and histomorphometric changes. A total of 70% of MSG-treated mice had poor nesting behavior. The treated mice also had more hyperphosphorylated tau protein in their cortical and hippocampus neurons. Glutamate and glutamine levels in the brain increased with MSG, and dose-dependent mixed horizontal locomotor, grooming, and anxiety responses reduced. MSG treatment significantly decreased phospho-CREB protein levels, supporting the idea that neurons were harmed, despite the increased CREB mRNA expression. High MSG doses drastically lower brain tissue and serum serotonin levels. In conclusion, MSG showed AD-like pathology, neuronal atrophy, and short-term memory impairment. Further research with a longer time span and deeper behavioral characterization is needed.Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier [CRD42022371502].

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Section: Introductionmentioning

confidence: 99%

A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer’s disease-like animal model

Ankul,

Chandran,

Anuragh

et al. 2023

Front. Pharmacol.

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One-pot Microwave Synthesis of Cobalt, Nitrogen, and Sulfur Co-Doped Carbon Quantum Dots for Efficient Monosodium Glutamate Determination in Food Samples

Hamid,

Elagamy,

Gamal

et al. 2024

Food Anal. Methods

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The synthesis of cobalt, nitrogen and sulfur co doped carbon quantum dots (Co-NS-CQDs) has become a subject of significant research interest. These CQDs were produced using a single-step microwave method, which is considered environmentally friendly, and the entire process was completed in just 90 seconds. In this synthesis, citric acid was utilized as the carbon source, methionine served as the source for both nitrogen and sulfur, and cobaltous acetate was used to introduce cobalt ions into the CQDs structure. The synthesized carbon quantum dots (CQDs) exhibit a narrow size distribution and a high quantum yield of 51.5%, which is notably superior to non-metal-doped CQDs with a yield of 38%. Characterization of these CQDs was performed using different techniques such as transmission electron microscopy (TEM), high-resolution TEM (HRTEM), Fourier transformation infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The developed CQDs have blue luminescence at emission wavelength 438 nm after excitation at 350 nm. Different factors affecting the CQDs synthesis including dialysis duration, reaction time and reaction temperature. These CQDs were utilized as a probe for the detection of monosodium glutamate (MSG) in various food products. The intensity of the fluorescence of the CQDs showed a direct and linear increase with the concentration of MSG within the range of 25–250 µg/mL. The detection and quantitation limits for MSG were 2.78 µg/mL and 8.44 µg/mL, respectively. Additionally, the developed method is environmentally friendly, as confirmed by assessments using the analytical Eco scale, Green Analytical Procedure Index (GAPI), and Analytical Greenness calculator (Agree). The proposed method presents several advantages over other reported methods in terms of convenience, rapid response, and attainment of accurate and precise results.

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Applications of metal complexes in analytical chemistry: A review article

Elattar,

El-Malla,

Kamal

et al. 2024

Coordination Chemistry Reviews

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Spectrophotometric determination of monosodium glutamate in instant noodles’ seasonings and Chinese salt by ligand exchange complexation

Cited by 6 publications

References 37 publications

A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer’s disease-like animal model

A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer’s disease-like animal model

One-pot Microwave Synthesis of Cobalt, Nitrogen, and Sulfur Co-Doped Carbon Quantum Dots for Efficient Monosodium Glutamate Determination in Food Samples

Applications of metal complexes in analytical chemistry: A review article

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