Spectroscopic investigation of new water soluble and complexes for the substrate binding models of xylose/glucose isomerases

Patra, Anirban; Bera, Manindranath

doi:10.1016/j.carres.2013.12.002

Cited by 16 publications

(6 citation statements)

References 68 publications

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“…We deem the loss of catalytic activity to two reasons, the inhibition effect of inhibitory factors (such as furfural) and the competition effect of other potential substrates. For instance, the glucose isomerase has been shown being capable of utilizing both D-glucose and D-xylose (Patra and Bera, 2014). To validate our hypothesis, we mimicked the hydrolysate by adding D-xylose to D-glucose to the same final concentrations.…”

Section: Producing D-allulose From Corn Stalkmentioning

confidence: 90%

Produce D-allulose from non-food biomass by integrating corn stalk hydrolysis with whole-cell catalysis

Jia

Zhang²,

Zhao³

et al. 2023

Front. Bioeng. Biotechnol.

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D-allulose is a high-value rare sugar with many health benefits. D-allulose market demand increased dramatically after approved as generally recognized as safe (GRAS). The current studies are predominantly focusing on producing D-allulose from either D-glucose or D-fructose, which may compete foods against human. The corn stalk (CS) is one of the main agricultural waste biomass in the worldwide. Bioconversion is one of the promising approach to CS valorization, which is of significance for both food safety and reducing carbon emission. In this study, we tried to explore a non-food based route by integrating CS hydrolysis with D-allulose production. Firstly we developed an efficient Escherichia coli whole-cell catalyst to produce D-allulose from D-glucose. Next we hydrolyzed CS and achieved D-allulose production from the CS hydrolysate. Finally we immobilized the whole-cell catalyst by designing a microfluidic device. Process optimization improved D-allulose titer by 8.61 times, reaching 8.78 g/L from CS hydrolysate. With this method, 1 kg CS was finally converted to 48.87 g D-allulose. This study validated the feasibility of valorizing corn stalk by converting it to D-allulose.

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Section: Producing D-allulose From Corn Stalkmentioning

confidence: 90%

Produce D-allulose from non-food biomass by integrating corn stalk hydrolysis with whole-cell catalysis

Jia

Zhang²,

Zhao³

et al. 2023

Front. Bioeng. Biotechnol.

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“…The most important coordination modes of the carboxylate groups are monodentate, syn‐syn bidentate, syn‐anti bidentate and anti‐anti bidentate [46,47] . In our laboratory, we have found that several di‐ and multinuclear Cu(II), Ni(II), Zn(II), Co(II) and Mn(II) complexes of carboxylate‐based multidentate ligands have exhibited the excellent binding interactions towards the biologically significant substrates such as DNA, BSA and different monosaccharides, in solution [48–54] . Recently, we have reported the synthesis, characterization, X‐ray crystal structure and phosphatase‐like activity of tetranuclear complexes of iron(III), zinc(II) and nickel(II) by utilizing carboxylate‐based multidentate ligands with appealing coordination chemistry [55,56] .…”

Section: Introductionmentioning

confidence: 94%

“…[46,47] In our laboratory, we have found that several diand multinuclear Cu(II), Ni(II), Zn(II), Co(II) and Mn(II) complexes of carboxylate-based multidentate ligands have exhibited the excellent binding interactions towards the biologically significant substrates such as DNA, BSA and different monosaccharides, in solution. [48][49][50][51][52][53][54] Recently, we have reported the synthesis, characterization, X-ray crystal structure and phosphatase-like activity of tetranuclear complexes of iron(III), zinc(II) and nickel(II) by utilizing carboxylate-based multidentate ligands with appealing coordination chemistry. [55,56] In this article, we report anthracene-appended carboxylate containing tridentate ligand, H 2 acpa which upon reaction with Cu((II), Mn(II) and Zn(II) salts, yields new mononuclear complexes, [Cu-…”

Section: Introductionmentioning

confidence: 99%

Cu(II), Mn(II) and Zn(II) Complexes of Anthracene‐Affixed Carboxylate‐Rich Tridentate Ligand: Synthesis, Structure, Spectroscopic Investigation and Their DNA Binding Profile

et al. 2022

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Anthracene-affixed carboxylate-rich tridentate ligand containing three new mononuclear complexes, [Cu(acpa)(H 2 O) 2 ]⋅H 2 O (1), [Mn(acpa)(H 2 O) 2 ] (2) and [Zn(acpa)(H 2 O) 2 ] (3) (H 2 acpa = 3-(anthracene-9-ylmethyl-carboxymethyl-amino)-propionic acid), have been synthesized and characterized by various analytical and spectral methods. In methanol, complexes 1-3 have been prepared by carrying out reaction of the ligand H 2 acpa with stoichiometric amounts of CuSO 4 ⋅ 5H 2 O, MnSO 4 ⋅H 2 O and ZnSO 4 ⋅ 7H 2 O respectively, in the presence of NaOH at ambient temperature. The X-ray crystal structure analysis reveals that complex 1 consists of a distorted square pyramidal copper center, coordinated to one acpa 2À ligand in a tridentate manner (N,O,O) and two exogenous water molecules. On the other hand, the molecular structures of complexes 2 and 3, optimized by DFT method indicate that their core arrangements around the metal centers are similar to that of 1. In solution, the coordination phenomena of Cu((II), Mn(II) and Zn(II) ions with the ligand H 2 acpa and the structural features of the complexes have been authenticated by UV-Vis and fluorescence titration experiments. The composition of the M II /acpa 2À complexes (M = Cu, Mn, Zn) in 1-3 has been observed to be 1 : 1, based on the UV-Vis/fluorescence titration results which are further supported by X-ray crystallography and DFT calculation. Complexes 1-3 are investigated for their binding affinity towards Calf Thymus (CT) DNA in solution at pH ∼ 7.5 by UV-Vis and fluorescence spectroscopic methods. From the electronic absorption spectral studies, it has been found that the DNA binding constants of 1-3 are (5.67 � 0.32) × 10 4 M À 1 , (2.35 � 0.26) × 10 4 M À 1 and (2.49 � 0.33) × 10 4 M À 1 , respectively, following the order 1 > 3 > 2. Measurements of viscosity of DNA in the absence and presence of the metal complexes suggest that all three complexes interact with DNA through partial intercalative mode.

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“…It has also given rise to many new techniques, including Magnetic Resonance Spectrometry (MRS), Nuclear Magnetic Resonance Imaging (MRI), Functional MRI (fMRI), Diffusion MRI (dMRI), and Diffusion Tensor Imaging (DTI) [1][2][3][4][5] . These NMR techniques find widespread applications in fields such as chemistry, biology, agriculture, and medicine [6][7][8][9] . With the ability to analyse metabolites, detect the structures of DNA, RNA, and proteins, and visualize human internal organs/serum without ionizing radiation, these techniques are truly versatile and valuable [10][11][12][13][14] .…”

Section: Overview Of Nmr Techniquesmentioning

confidence: 99%

Mathematical and Statistical Review of NMR Time Domain Data Pre-Processing

Jiang

2023

Preprint

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Nuclear Magnetic Resonance (NMR) and its various forms are extensively utilized in both research and clinical settings to analyse molecules. NMR data pre-processing, while essential to NMR data analysis, can be uniquely complex. Despite the availability of software tools, understanding these processes can be challenging, complicating the selection of appropriate pre-processing steps. In this review, we elucidate pre-processing steps in the time domain from a mathematical and statistical perspective, explaining direct current offset removal, eddy current correction, shift and linear prediction, weighting, zero filling, and domain transformation using plain language and fundamental mathematical formulas. Our objective is to clarify these processes in simple terms and provide general guidance.

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Spectroscopic investigation of new water soluble and complexes for the substrate binding models of xylose/glucose isomerases

Cited by 16 publications

References 68 publications

Produce D-allulose from non-food biomass by integrating corn stalk hydrolysis with whole-cell catalysis

Produce D-allulose from non-food biomass by integrating corn stalk hydrolysis with whole-cell catalysis

Cu(II), Mn(II) and Zn(II) Complexes of Anthracene‐Affixed Carboxylate‐Rich Tridentate Ligand: Synthesis, Structure, Spectroscopic Investigation and Their DNA Binding Profile

Mathematical and Statistical Review of NMR Time Domain Data Pre-Processing

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