Spectroscopic studies of self-assembled TPPS4nanostructures in aqueous solutions: The role of serum albumin and pH

Valančiūnaitė, Jurga; Žerebcova, Jelena; Bagdonas, Saulius; Streckyte, Giedre; Rotomskis, Ričardas

doi:10.3952/lithjphys.44105

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…In acidic medium, a red-shift in the Soret bands to 433 nm and the presence of only three Q-bands at 546, 593 and 645 nm was observed. This indicates the formation of one-dimensional ordered arrangements called J-aggregates23 characteristic of di-protonated (H + ) 2 TPPS 4 in line with reported studies 24. It has been reported that the presence of nitrogen atoms in TPPS 4 permits the protonation of the two pyrrolic nitrogens of TPPS 4 thereby changing the spectra and energetic properties of the porphyrin.…”

Section: Resultssupporting

confidence: 86%

Synthesis of meso-tetra-(4-sulfonatophenyl) porphyrin (TPPS4) – CuInS/ZnS quantum dots conjugate as an improved photosensitizer

Tsolekile

Ncapayi

Obiyenwa

et al. 2019

IJN

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Background Metal-free, water-soluble and highly stable meso-tetra-(4-sulfonatophenyl) porphyrin (TPPS 4 ) has been studied for their singlet oxygen quantum yield. However, TPPS 4 suffers from inherent shortcomings. To address these, TPPS 4 was conjugated to ternary copper indium sulphide/ zinc sulphide (CuInS 2 /ZnS) quantum dots (QDs). Purpose We herein report for the first time the synthesis of TPPS 4 –CuInS/ZnS QDs conjugate as an improved photosensitizer. Methods Water-soluble TPPS 4 was synthesized from tetraphenylporphyrin (TPPH 2 ) after silica-gel purification. The CuInS/ZnS QDs were synthesized by hydrothermal method at a Cu:In ratio of 1:4. The porphyrin–QDs conjugate was formed via the daggling sulfonyl bond of the porphyrin and amine bond of the QDs. The effect of pH on the optical properties of TPPS 4 was evaluated. The effect of Zn:Cu + In ratio on the ZnS shell passivation was examined to reduce structural defects on the as-synthesized QDs. Results: Various spectroscopic techniques were used to confirm the successful conversion of the organic TPPH 2 to water-soluble TPPS 4 . The singlet oxygen generation evaluation shows an improved singlet oxygen quantum yield from 0.19 for the porphyrin (TPPS 4 ) alone to 0.69 after conjugation (CuInS/ZnS-TPPS 4 ) with an increase in the reaction rate constant (k (s-1)).

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Section: Resultssupporting

confidence: 86%

Synthesis of meso-tetra-(4-sulfonatophenyl) porphyrin (TPPS4) – CuInS/ZnS quantum dots conjugate as an improved photosensitizer

Tsolekile

Ncapayi

Obiyenwa

et al. 2019

IJN

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“…The influence of proteins on the formation of J-aggregates of TPPS in aqueous acid solution (pH < 2) has been investigated [19,20,[26][27][28][29]. In the present work, we aim to investigate the interaction of TPPS with BSA in physiological environment (pH 7.4).…”

Section: Introductionmentioning

confidence: 99%

“…The formation of TPPS J-aggregates was reported occurring not only in pure aqueous medium but also in mixed solutions such as surfactants [22][23][24][25], proteins [19,20,[26][27][28][29], polypeptides [30,31], and cyclodextrins [32] at higher acidity (pH < 2).…”

Section: Introductionmentioning

confidence: 99%

Deep UV sensing of the interaction of porphyrin with bovine serum albumin protein

Li¹,

Seeger²

2009

Sensors and Actuators B: Chemical

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Deep UV sensing of the interaction of porphyrin with bovine serum albumin protein Deep UV sensing of the interaction of porphyrin with bovine serum albumin protein AbstractThe interaction of meso-tetrakis(p-sulfonatophenyl)porphyrin (TPPS) with bovine serum albumin (BSA) in neutral solution (pH 7.4) has been studied by means of absorption, steady-state fluorescence and time-resolved fluorescence spectroscopy. The formation of TPPS-BSA complex was monitored by spectroscopic characteristic changes in Soret band absorption and fluorescence emission of TPPS. Applying the time-correlated single-photon counting (TCSPC) method, BSA-TPPS interaction was also investigated by the fluorescence lifetime of tryptophan residues in BSA. The results demonstrate that deep UV laser-based fluorescence lifetime microscopy is useful for sensitive identification of protein interaction using intrinsic fluorescence. demonstrate that deep UV laser-based fluorescence lifetime microscopy is useful for sensitive identification of protein interaction using intrinsic fluorescence.

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Interaction of meso-tetrakis(4-sulphonatophenyl)porphine with chitosan in aqueous solutions

Synytsya

Blafkova

et al. 2007

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Spectroscopic studies of self-assembled TPPS₄nanostructures in aqueous solutions: The role of serum albumin and pH

Cited by 5 publications

References 18 publications

<p>Synthesis of meso-tetra-(4-sulfonatophenyl) porphyrin (TPPS<sub>4</sub>) – CuInS/ZnS quantum dots conjugate as an improved photosensitizer</p>

<p>Synthesis of meso-tetra-(4-sulfonatophenyl) porphyrin (TPPS<sub>4</sub>) – CuInS/ZnS quantum dots conjugate as an improved photosensitizer</p>

Deep UV sensing of the interaction of porphyrin with bovine serum albumin protein

Interaction of meso-tetrakis(4-sulphonatophenyl)porphine with chitosan in aqueous solutions

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