An efficient method for achieving ultra-broadband near-infrared signal amplification is proposed employing potential Pr3+ doped UV-sensitive germanium tellurite (NZPGT) glass fiber. The corresponding 1D2 → 1G4 transition emission covers from 1280 to 1680 nm with a full-width at half-maximum of 140 nm, and the associated emission cross-sections at 1390 and 1485 nm are derived to be 2.62 × 10−21 and 7.41 × 10−21 cm2, respectively. Large emission cross-section profile of Pr3+ in NZPGT glasses reveals that effective broadband amplification, especially at E- and S-band, is reasonable to be expected. Practicable operating mechanism of potential Pr3+ doped NZPGT glass fiber offers favorable prospects for rare-earth ion single-doped ultra-broadband signal amplifier.